Selected Publications


 

Invited commentary:  Nakamura, Hitomi.; Balskus, Emily P. “Using Chemical Knowledge to Uncover New Biological Function: Discovery of the Cylindrocyclophane Biosynthetic Pathway” Synlett, e-First article.

Brotherton, Carolyn A.; Balskus, Emily P. “A Prodrug Mechanism is Involved in Colibactin Biosynthesis and Cytotoxicity” Journal of the American Chemical Society, 2013, 135, 3359–3362.

 


 

Craciun, Smaranda; Balskus, Emily P. “Microbial Conversion of Choline to Trimethylamine Requires a Glycyl Radical Enzyme” Proceedings of the National Academy of Sciences USA 2012, 109, 21307–21312.

 


 

Nakamura, Hitomi; Hamer, Hilary A.; Sirasani, Gopal; Balskus, Emily P. “Cylindrocyclophane Biosynthesis Involves Functionalization of an Unactivated Carbon Center” Journal of the American Chemical Society 2012, 134, 18518–18521.

Postdoctoral Work:

Balskus, Emily P.; Case, Rebecca J.; Walsh, Christopher T. “The Biosynthesis of Cyanobacterial Sunscreen Scytonemin in Microbial Mat Communities” FEMS Microbiology Ecology 2011, 77, 322–332.

Balskus, Emily P.; Walsh, Christopher T. “The Genetic and Molecular Basis for Sunscreen Biosynthesis in Cyanobacteria” Science 2010, 329, 1653–1656.  Highlighted as a Science Express article, in The New Scientist online, and in Chemical & Engineering News 2010, 88, 59.

Balskus, Emily P.; Walsh, Christopher T. “An Enzymatic Cyclopentyl[b]indole Formation Involved in Scytonemin Biosynthesis” Journal of the American Chemical Society 2009, 131, 14648–14649.

Balskus, Emily P.; Walsh, Christopher T. “Investigating the Initial Steps in the Biosynthesis of Cyanobacterial Sunscreen Scytonemin” Journal of the American Chemical Society 2008, 130, 15260–15261.

Graduate Work:

Groll, Michael; Balskus, Emily P.; Jacobsen, Eric N. “Structural Analysis of Spiro beta-Lactone Proteasome Inhibitors” Journal of the American Chemical Society 2008, 130, 14981­–14983.

Balskus, Emily P.; Jacobsen, Eric N. “Asymmetric Catalysis of the Transannular Diels-Alder Reaction” Science 2007, 317, 1736–1740. Highlighted in Chemistry World 2007, 4, 33 and Chemical & Engineering News 2007, 85, 17.

Balskus, Emily P.; Jacobsen, Eric N. “Development of alpha,beta-Unsaturated, beta-Silyl Imide Substrates for Enantioselective Conjugate Additions: Application to the Total Synthesis of (+)-Lactacystin and the Discovery of a New Proteasome Inhibitor” Journal of the American Chemical Society 2006, 128, 6810–6811.