Dr. Mandl joined the Boston Children's Hospital Computational Health Informatics Program (CHIP) in 1995. Mandl's work at the intersection of population and individual health has had a unique, sustained influence on the developing field of biomedical informatics. His Presidential Early Career Award for Scientists and Engineers was for pioneering real time biosurveillance, tracking infections and detecting outbreaks with diverse data. Mandl has long advocated for patient participation in producing and accessing data. He created the first personal health systems, crowdsourced knowledge from online patient networks, and advanced participatory medicine and engagement in clinical trials. Cognizant of the limitations of extant electronic health record systems, Mandl developed a widely adopted, highly influential approach (SMART)--substitutable iPHone-like apps that run universally on health IT systems. SMART lets innovators reach market scale and patients and doctors access an “app store for health.” Mandl uses his open source inventions to lead large EHR research networks--he is principal investigator of the Scalable Collaborative Infrastructure for a Learning Health System across Boston hospitals and nationally. Recognized teaching, Mandl received the Clifford A. Barger Award for top mentors at Harvard Medical School. He was advisor to two Directors of the CDC and chaired the Board of Scientific Counselors of the NIH’s National Library of Medicine. His clinical training and experience is in pediatrics and pediatric emergency medicine. Dr. Mandl has been elected to multiple honor societies including the American Society for Clinical Investigation, Society for Pediatric Research, American College of Medical Informatics and American Pediatric Society. He is a recent recipient of the Donald A.B. Lindberg Award for Innovation in Informatics.