<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Cutrona, S. L.</style></author><author><style face="normal" font="default" size="100%">Choudhry, N. K.</style></author><author><style face="normal" font="default" size="100%">Stedman, M.</style></author><author><style face="normal" font="default" size="100%">Servi, A.</style></author><author><style face="normal" font="default" size="100%">Liberman, J. N.</style></author><author><style face="normal" font="default" size="100%">Brennan, T.</style></author><author><style face="normal" font="default" size="100%">Fischer, M. A.</style></author><author><style face="normal" font="default" size="100%">Brookhart, M. A.</style></author><author><style face="normal" font="default" size="100%">Shrank, W. H.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Physician effectiveness in interventions to improve cardiovascular medication adherence: a systematic review</style></title><secondary-title><style face="normal" font="default" size="100%">J Gen Intern Med</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2010</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Oct</style></date></pub-dates></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.ncbi.nlm.nih.gov/pubmed/20464522</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">10</style></number><edition><style face="normal" font="default" size="100%">2010/05/14</style></edition><volume><style face="normal" font="default" size="100%">25</style></volume><pages><style face="normal" font="default" size="100%">1090-6</style></pages><isbn><style face="normal" font="default" size="100%">1525-1497 (Electronic)0884-8734 (Linking)</style></isbn><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">BACKGROUND: Medications for the prevention and treatment of cardiovascular disease save lives but adherence is often inadequate. The optimal role for physicians in improving adherence remains unclear. OBJECTIVE: Using existing evidence, we set the goal of evaluating the physician's role in improving medication adherence. DESIGN: We conducted systematic searches of English-language peer-reviewed publications in MEDLINE and EMBASE from 1966 through 12/31/2008. SUBJECTS AND INTERVENTIONS: We selected randomized controlled trials of interventions to improve adherence to medications used for preventing or treating cardiovascular disease or diabetes. MAIN MEASURES: Articles were classified as either (1) physician &quot;active&quot;-a physician participated in designing or implementing the intervention; (2) physician &quot;passive&quot;-physicians treating intervention group patients received patient adherence information while physicians treating controls did not; or (3) physicians noninvolved. We also identified studies in which healthcare professionals helped deliver the intervention. We did a meta-analysis of the studies involving healthcare professionals to determine aggregate Cohen's D effect sizes (ES). KEY RESULTS: We identified 6,550 articles; 168 were reviewed in full, 82 met inclusion criteria. The majority of all studies (88.9%) showed improved adherence. Physician noninvolved studies were more likely (35.0% of studies) to show a medium or large effect on adherence compared to physician-involved studies (31.3%). Among interventions requiring a healthcare professional, physician-noninvolved interventions were more effective (ES 0.47; 95% CI 0.38-0.56) than physician-involved interventions (ES 0.25; 95% CI 0.21-0.29; p &lt; 0.001). Among physician-involved interventions, physician-passive interventions were marginally more effective (ES 0.29; 95% CI 0.22-0.36) than physician-active interventions (ES 0.23; 95% CI 0.17-0.28; p = 0.2). CONCLUSIONS: Adherence interventions utilizing non-physician healthcare professionals are effective in improving cardiovascular medication adherence, but further study is needed to identify the optimal role for physicians.</style></abstract><accession-num><style face="normal" font="default" size="100%">20464522</style></accession-num><notes><style face="normal" font="default" size="100%">Cutrona, Sarah LChoudhry, Niteesh KStedman, MargaretServi, AmberLiberman, Joshua NBrennan, TroyenFischer, Michael ABrookhart, M AlanShrank, William HAG-027400/AG/NIA NIH HHS/United StatesHL-090505/HL/NHLBI NIH HHS/United StatesResearch Support, N.I.H., ExtramuralUnited StatesJournal of general internal medicineJ Gen Intern Med. 2010 Oct;25(10):1090-6. Epub 2010 May 13.</style></notes><custom2><style face="normal" font="default" size="100%">2955481</style></custom2><auth-address><style face="normal" font="default" size="100%">Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA 02120, USA. slcutrona@gmail.com</style></auth-address></record></records></xml>