<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Walsworth, R. L.</style></author><author><style face="normal" font="default" size="100%">Patz, S.</style></author><author><style face="normal" font="default" size="100%">Rosen, M. S.</style></author><author><style face="normal" font="default" size="100%">Mair, R. W.</style></author><author><style face="normal" font="default" size="100%">Tsai, L. L.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">An open-access, very-low-field MRI system for posture-dependent He-3 human lung imaging</style></title><secondary-title><style face="normal" font="default" size="100%">JOURNAL OF MAGNETIC RESONANCE</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2008</style></year><pub-dates><date><style  face="normal" font="default" size="100%">AUG</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">2</style></number><volume><style face="normal" font="default" size="100%">193</style></volume><pages><style face="normal" font="default" size="100%">274-285</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;We describe the design and operation of an open-access, very-low-field, magnetic resonance imaging (MRI) system for in vivo hyperpolarized He-3 imaging of the human lungs. This system permits the study of lung function in both horizontal and upright postures, a capability with important implications in pulmonary physiology and clinical medicine, including asthma and obesity. The imager uses a bi-planar B-0 coil design that produces an optimized 65 G (6.5 mT) magnetic field for He-3 MRI at 210 kHz. Three sets of bi-planar coils produce the x, y. and z magnetic field gradients while providing a 79-cm inter-coil gap for the imaging subject. We use solenoidal Q-spoiled RE coils for operation at low frequencies, and are able to exploit insignificant sample loading to allow for pre-tuning/matching schemes and for accurate pre-calibration of flip angles. We obtain sufficient SNR to acquire 2D He-3 images with up to 2.8 mm resolution, and present initial 2D and 3D He-3 images of human lungs in both supine and upright orientations. H-1 MRI can also be performed for diagnostic and calibration reasons. Published by Elsevier Inc.&lt;/p&gt;
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