This is the list of 145 significantly (p<0.001, >2 fold) up-regulated genes in the S+P-derived motor neurons (GFP+, FACS purified, top) and the 5 genes significantly down-regulated in S+P MNs (below and right). Displayed as fold change.
Please see update (left panel) for added information.
| Gene | S+P MN vs. S+P non-MN |
| AC004455.1 | 43.10 |
| AC011738.1 | 41.71 |
| CD28 | 36.64 |
| TMC3 | 31.52 |
| RET | 28.75 |
| FABP6 | 26.09 |
| AC007392.1 | 25.23 |
| MNX1 | 24.73 |
| RXRG | 20.62 |
| ASPHD1 | 20.37 |
| LHFPL4 | 18.83 |
| PAX2 | 18.67 |
| LRRC4C | 18.29 |
| DLGAP2 | 18.14 |
| RP11-307P5.2 | 18.19 |
| RP11-562P17.1 | 17.83 |
| HECW1 | 17.11 |
| CHAT | 15.67 |
| SCML4 | 15.38 |
| EEF1DP3 | 15.26 |
| LEMD1 | 15.19 |
| SPOCK3 | 15.10 |
| FAIM2 | 15.01 |
| STMN2 | 14.31 |
| AP000880.1 | 13.98 |
| PSD2 | 13.88 |
| GLRA2 | 13.68 |
| ACTL6B | 13.45 |
| ADCYAP1 | 13.46 |
| KCND2 | 13.46 |
| SCN2A | 13.22 |
| SLC5A7 | 12.85 |
| SCN3A | 12.49 |
| STMN4 | 12.32 |
| KCNIP1 | 12.22 |
| CCBE1 | 12.08 |
| MYT1L | 11.99 |
| SVOP | 11.95 |
| RP11-263A24.1 | 11.86 |
| FAM57B | 11.79 |
| NXPH4 | 11.76 |
| SGIP1 | 11.65 |
| MAST1 | 11.53 |
| AKAP6 | 11.47 |
| SST | 11.43 |
| FRY | 11.27 |
| SYT4 | 11.24 |
| AC093310.1 | 11.10 |
| GPX3 | 11.05 |
| ISL1 | 10.94 |
| SLC24A3 | 10.95 |
| AP006285.5 | 10.81 |
| GNG3 | 10.81 |
| ZNF385D | 10.79 |
| CHL1 | 10.76 |
| OLFM3 | 10.64 |
| PDZRN4 | 10.56 |
| P2RX3 | 10.36 |
| SAMD5 | 10.35 |
| GPR83 | 10.31 |
| CDK5R2 | 10.00 |
| TRIM67 | 9.84 |
| SLC18A3 | 9.72 |
| SLIT3 | 9.69 |
| FAM123C | 9.69 |
| SLC1A2 | 9.60 |
| CNTN2 | 9.60 |
| MYT1 | 9.59 |
| RTN1 | 9.54 |
| PLCL1 | 9.42 |
| NRXN1 | 9.36 |
| AC011306.2 | 9.35 |
| RP11-768G7.2 | 9.29 |
| DCX | 9.29 |
| L1CAM | 9.18 |
| NCAM1 | 9.15 |
| SNAP91 | 9.11 |
| ONECUT2 | 9.11 |
| IGLON5 | 9.02 |
| KIAA1045 | 8.96 |
| SV2C | 8.95 |
| RP11-115O13.1 | 8.92 |
| FSTL4 | 8.85 |
| NRG1 | 8.82 |
| MAPT | 8.82 |
| SYN3 | 8.70 |
| ONECUT1 | 8.67 |
| NMNAT2 | 8.61 |
| DNER | 8.54 |
| ISLR2 | 8.47 |
| SMPD3 | 8.46 |
| AC113209.3 | 8.42 |
| RAB3A | 8.42 |
| STX1B | 8.44 |
| CDH12 | 8.29 |
| SEZ6L | 8.10 |
| Sept5 | 8.00 |
| GRIN2A | 7.99 |
| RCAN2 | 7.92 |
| CASZ1 | 7.88 |
| CORO2A | 7.86 |
| CRABP1 | 7.74 |
| GRIA2 | 7.74 |
| DUSP8 | 7.72 |
| PAK7 | 7.71 |
| INA | 7.61 |
| BRUNOL4 | 7.58 |
| SNAP25 | 7.58 |
| PAX5 | 7.57 |
| NOS1AP | 7.55 |
| DCC | 7.48 |
| VSTM2A | 7.46 |
| SRCIN1 | 7.39 |
| KIAA1409 | 7.36 |
| PRPH | 7.32 |
| ELAVL3 | 7.30 |
| ELAVL4 | 7.28 |
| PLXNA4 | 7.21 |
| SPOCK2 | 7.14 |
| SLC7A14 | 7.07 |
| CTNNA2 | 7.08 |
| RP11-384F7.1 | 7.03 |
| PHOX2B | 6.97 |
| NRXN3 | 6.89 |
| REEP1 | 6.81 |
| PCDH15 | 6.81 |
| CADPS | 6.80 |
| PPAPR3 | 6.73 |
| DRD2 | 6.68 |
| PAK3 | 6.60 |
| ATCAY | 6.57 |
| SLITRK1 | 6.58 |
| GNAO1 | 6.57 |
| LRP1B | 6.54 |
| ODZ2 | 6.44 |
| TNRC4 | 6.39 |
| MAGI2 | 6.39 |
| ATP8A1 | 6.34 |
| EBF3 | 6.30 |
| DLG2 | 6.14 |
| CRABP2 | 6.00 |
| NCAN | 5.93 |
| NEUROD1 | 5.92 |
| LRRTM4 | 5.86 |
| BMP3 | Not Detected in Neg. fraction |
| Gene | Down-regulated in S+P MNs |
| GDF3 | 6.58 |
| JUB | 7.30 |
| FAM181A | 14.08 |
| DLK1 | 6.93 |
| NTRK2 | 8.23 |
Data generated in Expression Plot.