Research in the Balskus Lab:

Discovering, Understanding, and Manipulating Microbial Chemistry


Latest Lab News

A New Strategy for Enzyme Discovery in Microbiomes

February 12, 2017

Our recent Science paper reports the development of chemically guided functional profiling and the discovery of a new glycyl radical enzyme in human gut microbes that metabolizes a host-derived amino acid. Congratulations to Ben, Yolanda, Spencer, Ana, and Jonathan, and thank you to our wonderful collaborators Yifeng Wei (MIT), Eric Franzosa, and Curtis Huttenhower (Harvard School of Public Health, Broad Institute)!

New Insights Into Gut Bacterial Metabolism

September 16, 2016

A paper detailing our collaborative work with the Drennan lab at MIT to characterize the structure and mechanism of the disease-associated gut microbial enzyme choline trimethylamine-lyase (CutC) has appeared in Cell Chemical Biology. Congratulations to Sam B. and Michael!

Welcome New Lab Members

September 16, 2016

Welcome to Vayu Maini Rekdal, a graduate student from the MCO program who joined the Balskus Lab this summer, and Dr. Monica McCallum, a new postdoctoral researcher!