Our research examines structural and functional changes in the brain with aging and age-associated neurodegenerative disease. A primary focus of this work is to determine how the common decline in vascular health with advancing age contributes to neurodegenerative changes, cognitive attenuation and the development of Alzheimer’s disease and other dementias. We utilize structural and functional neuroimaging technology as a primary tool to measure subtle alterations in tissue integrity and physiology and how those changes relate to measures of cognitive function and systemic physiology. Through these studies, we hope to advance procedures for the clinical utilization of imaging technology in the diagnosis, characterization and tracking of neurodegenerative disease as well as towards advancing understanding of the pathological mechanisms that cause dementia.
Thank you to everyone who donated for the Walk to End Alzheimer’s! #WeBAnDTogether #teamwork t.co/pnK3dHGWpz
- The lab is participating in the Walk to End Alzheimer's this Sunday, September 23rd. Help us fundraise for the fight against Alzheimer's disease by clicking the link to donate! #WeBAnDTogether #AlzheimersAwarenessMonth 💜 t.co/okMMXnB5tW
Short timescale abnormalities in the states of spontaneous synchrony in the functional neural networks in Alzheimer's disease: t.co/N3sKIA3dTs t.co/av6xoo7JwS
Re-examining age-related differences in white matter microstructure with free-water corrected diffusion tensor imaging: t.co/Tokn46RrQi @JeanChenLab t.co/U9P8HZwSsN
- @ScottHayesPhD @DavidSalat Yes, agreed!