Our research examines structural and functional changes in the brain with aging and age-associated neurodegenerative disease. A primary focus of this work is to determine how the common decline in vascular health with advancing age contributes to neurodegenerative changes, cognitive attenuation and the development of Alzheimer’s disease and other dementias. We utilize structural and functional neuroimaging technology as a primary tool to measure subtle alterations in tissue integrity and physiology and how those changes relate to measures of cognitive function and systemic physiology. Through these studies, we hope to advance procedures for the clinical utilization of imaging technology in the diagnosis, characterization and tracking of neurodegenerative disease as well as towards advancing understanding of the pathological mechanisms that cause dementia.
Shades of white: diffusion properties of T1- and FLAIR-defined white matter signal abnormalities differ in stages from cognitively normal to dementia.
- Postdoctoral and research assistant positions are available in neuroimaging of mTBI and PTSD in the TRACTS group/Neuroimaging Research for Veterans Center at VA Boston. See: t.co/YLHWRI82yK for more information. Please RT, thank you!
- Imaging Brain Aging: Submissions are still being accepted for this special issue of @NeuroImage_EiC. t.co/w5apCmKFgI t.co/tZZSg9Kqni
- Imaging Brain Aging Special Issue of @NeuroImage_EiC now open for submissions! Thank you to all considering a contribution. #aging #brain #mri #fmri #memory #diffusion #vascular t.co/fsOuwE8EFL
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