Our research examines structural and functional changes in the brain with aging and age-associated neurodegenerative disease. A primary focus of this work is to determine how the common decline in vascular health with advancing age contributes to neurodegenerative changes, cognitive attenuation and the development of Alzheimer’s disease and other dementias. We utilize structural and functional neuroimaging technology as a primary tool to measure subtle alterations in tissue integrity and physiology and how those changes relate to measures of cognitive function and systemic physiology. Through these studies, we hope to advance procedures for the clinical utilization of imaging technology in the diagnosis, characterization and tracking of neurodegenerative disease as well as towards advancing understanding of the pathological mechanisms that cause dementia.
before, during, after.. My mind is bursting with science! Thank you @OHBM ! #OHBM17 t.co/0QM7NoXS3P
Congratulations to lab member Emily Lindemer who now has a PhD! t.co/rAdwiHwQCK
- Baycrest scientist Dr. Jean Chen appointed Canada Research Chair in Neuroimaging of Aging t.co/dwy6cbLWv0 @CRC_CRC t.co/DBkRPMrHdI
- Transcytosis may do most of the work in controlling the barrier between the blood and central nervous system t.co/voVMRipfHk t.co/pCU1j8XDMJ
- Two distinct classes of degenerative change linked to progression in MCI @jpcoutu87 t.co/SZmAcdbjD1