Publications

2020
Pirruccello JP, Bick A, Wang M, Chaffin M, Lubitz SA, Ellinor PT, Khera AV, Kathiresan S, Aragam KG. Analysis of cardiac magnetic resonance imaging traits in 29,000 individuals reveals shared genetic basis with dilated cardiomyopathy. bioRxiv. 2020.
Magudia K, Ng TS, Bick AG, Koster MA, Bay C, Rexrode KM, Smith SE, Weinstein DF. Parenting While in Training: A Comprehensive Needs Assessment of Residents and Fellows. Journal of Graduate Medical Education. 2020.
Pirruccello JP, Bick A, Chaffin M, Aragam KG, Choi SH, Lubitz SA, Ho CY, Ng K, Philippakis A, Ellinor PT, et al. Titin Truncating Variants in Adults Without Known Congestive Heart Failure. Journal of the American College of Cardiology. 2020;75 (10) :1239–1241.
2019
Bick AG, Akwo E, Robinson-Cohen C, Lee K, Lynch J, Assimes TL, DuVall S, Edwards T, Fang H, Freiberg MS, et al. Association of APOL1 Risk Alleles With Cardiovascular Disease in Blacks in the Million Veteran Program. Circulation. 2019;140 (12) :1031–1040.
Khetarpal SA, Qamar A, Bick AG, Fuster JJ, Kathiresan S, Jaiswal S, Natarajan P. Clonal Hematopoiesis of Indeterminate Potential Reshapes Age-Related CVD: JACC Review Topic of the Week. Journal of the American College of Cardiology. 2019;74 (4) :578–586.
Emdin CA, Khera AV, Aragam K, Haas M, Chaffin M, Klarin D, Natarajan P, Bick A, Zekavat SM, Nomura A, et al. DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes. Diabetes. 2019;68 (1) :226–234.
Bick AG, Pirruccello JP, Griffin GK, Gupta N, Gabriel S, Saleheen D, Libby P, Kathiresan S, Natarajan P. Genetic IL-6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis. Circulation. 2019.
Bao EL, Nandakumar SK, Liao X, Bick AG, Karjalainen J, Tabaka M, Gan OI, Havulinna A, Kiiskinen T, Lareau CA, et al. Genetic predisposition to myeloproliferative neoplasms implicates hematopoietic stem cell biology. bioRxiv. 2019 :790626.
Bick AG, Weinstock J, Nandakumar SK, Fulco CP, Leventhal MJ, Bao EL, Nasser J, Zekavat SM, Szeto MD, Laurie C, et al. Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes. bioRxiv. 2019 :782748.
Emdin CA, Haas M, Khera AV, Aragam K, Chaffin M, Jiang L, Wei W-Q, Feng Q, Karjalainen J, Havulinna A, et al. A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease. BioRxiv. 2019 :594523.
Fahed AC, Wang M, Homburger JR, Patel AP, Bick AG, Neben CL, Lai C, Brockman D, Philippakis A, Ellinor PT, et al. Polygenic background modifies penetrance of monogenic variants conferring risk for coronary artery disease, breast cancer, or colorectal cancer. medRxiv. 2019 :19013086.
Khera AV, Chaffin M, Wade KH, Zahid S, Brancale J, Xia R, Distefano M, Senol-Cosar O, Haas ME, Bick A, et al. Polygenic prediction of weight and obesity trajectories from birth to adulthood. Cell. 2019;177 (3) :587–596.
Pirruccello JP, Bick A, Friedman S, Chaffin M, Aragam KG, Choi SH, Lubitz SA, Ho C, Ng K, Philippakis A, et al. Prevalence and clinical importance of titin truncating variants in adults without known congestive heart failure. medRxiv. 2019 :19005058.
2018
Emdin CA, Khera AV, Chaffin M, Klarin D, Natarajan P, Aragam K, Haas M, Bick A, Zekavat SM, Nomura A, et al. Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease. Nature Communications. 2018;9 (1) :1613.
Magudia K, Bick A, Cohen J, Ng TS, Weinstein D, Mangurian C, Jagsi R. Childbearing and Family Leave Policies for Resident Physicians at Top Training Institutions. Jama. 2018;320 (22) :2372–2374.
Haas ME, Aragam KG, Emdin CA, Bick AG, Hemani G, Smith GD, Kathiresan S, for Pressure ICB, others. Genetic association of albuminuria with cardiometabolic disease and blood pressure. The American Journal of Human Genetics. 2018;103 (4) :461–473.
Zhang J-Y, Wang M, Tian L, Genovese G, Yan P, Wilson JG, Thadhani R, Mottl AK, Appel GB, Bick AG, et al. UBD modifies APOL1-induced kidney disease risk. Proceedings of the National Academy of Sciences. 2018;115 (13) :3446–3451.
2017
Bick AG, Wakimoto H, Kamer KJ, Sancak Y, Goldberger O, Axelsson A, DeLaughter DM, Gorham JM, Mootha VK, Seidman JG, et al. Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter. Proceedings of the National Academy of Sciences. 2017;114 (43) :E9096–E9104.
Jaiswal S, Natarajan P, Silver AJ, Gibson CJ, Bick AG, Shvartz E, McConkey M, Gupta N, Gabriel S, Ardissino D, et al. Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease. New England Journal of Medicine. 2017;377 (2) :111–121.
Esslinger U, Garnier S, Korniat A, Proust C, Kararigas G, Müller-Nurasyid M, Empana J-P, Morley MP, Perret C, Stark K, et al. Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy. PLoS One. 2017;12 (3).

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