What's stopping you from doing absolutely everything that your devious heart desires? The ability to flexibly control our behavior - particularly when it comes to rewarding things like food, sex, and drugs - has huge consequences for our long-term happiness and success. Though we are reasonably good at this as a species, dramatic individual differences in the capacity for self-control are readily apparent. In this class, we will examine the cognitive construct of self-control, its neurobiological underpinnings and sources of individual variation, and relationships to psychopathology.