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Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging can improve patient outcomes

Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging can improve patient outcomes

November 8, 2020
A large meta-analysis of patients who have had a stroke with unknown time of onset with a DWI-FLAIR or perfusion mismatch showed that intravenous alteplase resulted in better functional outcome at 90 days than placebo or standard care. A net benefit was observed for all functional outcomes despite an increased risk of symptomatic intracranial haemorrhage. Although there were more deaths with... Read more about Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging can improve patient outcomes