Novel Imaging Markers of Ischemic Cerebral Edema and Its Association with Neurological Outcome

Citation:

Kimberly TW, Battey TWK, Wu O, Singhal AB, Campbell BCV, Davis SM, Donnan GA, Sheth KN. Novel Imaging Markers of Ischemic Cerebral Edema and Its Association with Neurological Outcome. Acta Neurochir Suppl 2016;121:223-6. Copy at https://j.mp/2LxWLP8

Date Published:

2016

Abstract:

Ischemic cerebral edema (ICE) is a recognized cause of secondary neurological deterioration after large hemispheric stroke, but little is known about the scope of its impact. To study edema in less severe stroke, our group has developed several markers of cerebral edema using brain magnetic resonance imaging (MRI). These tools, which are based on categorical and volumetric measurements in serial diffusion-weighted imaging (DWI), are applicable to a wide variety of stroke volumes. Further, these metrics provide distinct volumetric measurements attributable to ICE, infarct growth, and hemorrhagic transformation. We previously reported that ICE independently predicted neurological outcome after adjustment for known risk factors. We found that an ICE volume of 11 mL or greater was associated with worse neurological outcome.
See also: Stroke
Last updated on 11/27/2019