Segmentation of cerebrovascular pathologies in stroke patients with spatial and shape priors

Citation:

Dalca AV, Sridharan R, Cloonan L, Fitzpatrick KM, Kanakis A, Furie KL, Rosand J, Wu O, Sabuncu M, Rost NS, Golland P. Segmentation of cerebrovascular pathologies in stroke patients with spatial and shape priors. Med Image Comput Comput Assist Interv 2014;17(Pt 2):773-80. Copy at https://j.mp/34SlKnU

Date Published:

2014

Abstract:

We propose and demonstrate an inference algorithm for the automatic segmentation of cerebrovascular pathologies in clinical MR images of the brain. Identifying and differentiating pathologies is important for understanding the underlying mechanisms and clinical outcomes of cerebral ischemia. Manual delineation of separate pathologies is infeasible in large studies of stroke that include thousands of patients. Unlike normal brain tissues and structures, the location and shape of the lesions vary across patients, presenting serious challenges for prior-driven segmentation. Our generative model captures spatial patterns and intensity properties associated with different cerebrovascular pathologies in stroke patients. We demonstrate the resulting segmentation algorithm on clinical images of a stroke patient cohort.
Last updated on 11/27/2019