Publications

2020

Z Inde, C Yapp et al., Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity, Biorxiv, doi: https://doi.org/10.1101/2020.09.13.276923

A Farkkila....C Yapp  et al., Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer, Nat. Comm. 11, 1459

S Rao,....C Yapp et al., Transcriptomic and Functional Screens Reveal MicroRNAs That Modulate Prostate Cancer Metastasis, Front. Oncol., https://doi.org/10.3389/fonc.2020.00292

JC Melms....C Yapp et al., Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity, Cancer Research,80, 798-810

G Gaglia, R Rashid, C Yapp et al., HSF1 phase transition mediates stress adaptation and cell fate decisions, Nat. Cel. Biol., 22, 151-158

2019 

ML Onozato*, C Yapp*,(* contributed equally) et al., Highly Multiplexed Fluorescence in Situ Hybridization for in Situ Genomics, J Molecular Diagnostics, 21:3, 390–407

S Saka,...C Yapp, et al., Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER, Nat. Biotech, 37(9), 1080

C Xu, C Yapp et al., Control of Synaptic Specificity by Establishing a Relative Preference for Synaptic Partners, Neuron, 103(5), 865

2018

JR Lin, ...C Yapp, et al., Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes, Elife, 11,7: e31657

< 2017

SB Hatch*, C Yapp*, (* contributed equally) et al., Assessing histone demethylase inhibitors in cells: lessons learned, Epigenetics and Chromatin, 10:9

A Kawamura, M Munzel, T Kojima, C Yapp et al., Highly Selective inhibition of histone demethylases by de novo macrocyclic peptides, Nature Communications, 8: 14773

M Niederhuber, C Yapp, et al., 2017, Superresolution microscopy of the β-carboxysome reveals a homogeneous matrix, ACS Chem Biol., 12(10), 2619

C Yapp, U Oppermann, A Price et al., 2016, H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis, Arthritis Res. Ther., 18(1):158

C Yapp, C Rogers, Pavel Savitsky et al., 2016, Frapid: achieving full automation of FRAP for chemical probe validation, Biomed. Opt. Express, 7(2):422-441

MK Kuzniarska, C Yapp, PA Hulley, 2016, Using fluorescence recovery after photobleaching to study gap junctional communication in vitro, Gap Junction Protocols, 1437:171-179

SG Dakin, FM Estrada, C Yapp et al., 2016, Inflammation activation and resolution in human tendon disease, Sci. Transl. Med., 7(311):173 

CL Sutherell, C Tallant, O Monteiro, C Yapp et al., 2016, Identificaton and development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex,  J. Med. Chem.

TM Grant, C Yapp et al., 2015, The Mechanical, structural, and compositional changes of tendon exposed to elastase, Ann. Biomed. Eng.

CC Thinnes, A Tumber, C Yapp et al., 2015, Betti Reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases, Chem. Commun.

M Philpott, CM Rogers, C Yapp, et al., 2014, Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching, Epigenetics & Chromatin

MK Kuzniarska, C Yapp et al., 2014, Functional assessment of gap junctions in monolayer and three-dimensional cultures of human tendon cells using fluorescence recovery after photobleaching. J. Biomed. Opt.

RJ Hopkinson*, A Tumber*, C Yapp* (* contributed equally) et al., 2013, 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation. Chemical Science

I Adekanmbi, NZ Baboldashti, C Yapp et al. 2013, A novel in vitro loading system for high frequency loading of cultured tendon fascicles. Med Eng Phys. 

U Tirlapur & C Yapp, 2011, Near Infrared Three-Dimensional Nonlinear Optical Monitoring of Stem Cell Differentiation. Optical  Fluorescence Microscopy

C Yapp & ASK Bin, 2008, Teaching Image Processing: A Two Step Process. Computer Applications in Engineering Education. 16(3):211-222

LB Leong & C Yapp, 2008, Dissipative Relativistic Standard Map. Chaos, Solitons & Fractals. 37(5): 1300-1304