Publications

    G. A. Alzamendi, et al., “Bayesian estimation of vocal function measures using laryngeal high-speed videoendoscopy and glottal airflow estimates: An in vivo case study,” The Journal of the Acoustical Society of America, vol. 147, no. 5, pp. EL434-EL439, 2020. Publisher's VersionAbstract
    This study introduces the in vivo application of a Bayesian framework to estimate subglottal pressure, laryngeal muscle activation, and vocal fold contact pressure from calibrated transnasal high-speed videoendoscopy and oral airflow data. A subject-specific, lumped-element vocal fold model is estimated using an extended Kalman filter and two observation models involving glottal area and glottal airflow. Model-based inferences using data from a vocally healthy male individual are compared with empirical estimates of subglottal pressure and reference values for muscle activation and contact pressure in the literature, thus providing baseline error metrics for future clinical investigations.
    M. Motie-Shirazi, et al., “Toward development of a vocal fold contact pressure probe: Sensor characterization and validation using synthetic vocal fold models,” Applied Sciences, vol. 9, no. 15, pp. 3002, 2019. Publisher's VersionAbstract
    Excessive vocal fold collision pressures during phonation are considered to play a primary role in the formation of benign vocal fold lesions, such as nodules. The ability to accurately and reliably acquire intraglottal pressure has the potential to provide unique insights into the pathophysiology of phonotrauma. Difficulties arise, however, in directly measuring vocal fold contact pressures due to physical intrusion from the sensor that may disrupt the contact mechanics, as well as difficulty in determining probe/sensor position relative to the contact location. These issues are quantified and addressed through the implementation of a novel approach for identifying the timing and location of vocal fold contact, and measuring intraglottal and vocal fold contact pressures via a pressure probe embedded in the wall of a hemi-laryngeal flow facility. The accuracy and sensitivity of the pressure measurements are validated against ground truth values. Application to in vivo approaches are assessed by acquiring intraglottal and VF contact pressures using a synthetic, self-oscillating vocal fold model in a hemi-laryngeal configuration, where the sensitivity of the measured intraglottal and vocal fold contact pressure relative to the sensor position is explored.