High-Speed Video

2011
M. Döllinger, J. B. Kobler, D. A. Berry, D. D. Mehta, G. Luegmair, and C. Bohr, “Experiments on analysing voice production: Excised (human, animal) and in vivo (animal) approaches,” Current Bioinformatics, vol. 6, no. 3, pp. 286-304, 2011. Publisher's Version Paper
D. D. Mehta, S. M. Zeitels, J. A. Burns, A. D. Friedman, D. D. Deliyski, and R. E. Hillman, “High-speed videoendoscopic analysis of relationships between cepstral-based acoustic measures and voice production mechanisms in patients undergoing phonomicrosurgery,” Proceedings of the American Laryngological Association. 2011.
D. D. Mehta, M. Zañartu, T. F. Quatieri, D. D. Deliyski, and R. E. Hillman, “Investigating acoustic correlates of human vocal fold vibratory phase asymmetry through modeling and laryngeal high-speed videoendoscopy,” The Journal of the Acoustical Society of America, vol. 130, pp. 3999-4009, 2011.Abstract

Vocal fold vibratory asymmetry is often associated with inefficient sound production through its impact on source spectral tilt. This association is investigated in both a computational voice production model and a group of 47 human subjects. The model provides indirect control over the degree of left-right phase asymmetry within a nonlinear source-filter framework, and high-speed videoendoscopy provides in vivo measures of vocal fold vibratory asymmetry. Source spectral tilt measures are estimated from the inverse-filtered spectrum of the simulated and recorded radiated acoustic pressure. As expected, model simulations indicate that increasing left-right phase asymmetry induces steeper spectral tilt. Subject data, however, reveal that none of the vibratory asymmetry measures correlates with spectral tilt measures. Probing further into physiological correlates of spectral tilt that might be affected by asymmetry, the glottal area waveform is parameterized to obtain measures of the open phase (open/plateau quotient) and closing phase (speed/closing quotient). Subjects' left-right phase asymmetry exhibits low, but statistically significant, correlations with speed quotient (r=0.45) and closing quotient (r=-0.39). Results call for future studies into the effect of asymmetric vocal fold vibration on glottal airflow and the associated impact on voice source spectral properties and vocal efficiency.

Paper
M. Zañartu, D. D. Mehta, J. C. Ho, G. R. Wodicka, and R. E. Hillman, “Observation and analysis of in vivo vocal fold tissue instabilities produced by nonlinear source-filter coupling: A case study,” The Journal of the Acoustical Society of America, vol. 129, pp. 326-339, 2011. Paper
D. D. Mehta, M. Zañartu, T. F. Quatieri, D. D. Deliyski, and R. E. Hillman, “Use of laryngeal high-speed videoendoscopy systems to study voice production mechanisms in human subjects,” Proceedings of the Acoustical Society of America, vol. 130, pp. 2439-2439, 2011.
2010
D. D. Mehta, M. Zañartu, T. F. Quatieri, D. D. Deliyski, and R. E. Hillman, “Acoustic correlates of human vocal fold vibratory phase asymmetry through modeling and laryngeal high-speed videoendoscopy,” Proceedings of the International Conference on Advances in Quantitative Laryngology, 2010.
S. S. Karajanagi, et al., “Assessment of canine vocal fold function after injection of a new biomaterial designed to treat phonatory mucosal scarring,” Proceedings of the American Broncho-Esophagological Association. 2010.
D. D. Mehta, R. E. Hillman, and T. F. Quatieri, “Impact of human vocal fold vibratory asymmetries on acoustic characteristics of sustained vowel phonation,” Massachusetts Institute of Technology, 2010. Thesis
D. D. Mehta, D. D. Deliyski, S. M. Zeitels, T. F. Quatieri, and R. E. Hillman, “Voice production mechanisms following phonosurgical treatment of early glottic cancer,” Annals of Otology, Rhinology, and Laryngology, vol. 119, pp. 1-9, 2010. Publisher's VersionAbstract

Objectives: Although near-normal conversational voices can be achieved with the phonosurgical management of earlyglottic cancer, there are still acoustic and aerodynamic deficits in vocal function that must be better understood to helpfurther optimize phonosurgical interventions. Stroboscopic assessment is inadequate for this purpose.Methods: A newly developed color high-speed videoendoscopy (HSV) system that included time-synchronized recordingsof the acoustic signal was used to perform a detailed examination of voice production mechanisms in 14 subjects.Digital image processing techniques were used to quantify glottal phonatory function and to delineate relationships betweenvocal fold vibratory properties and acoustic perturbation measures.Results: The results for multiple measurements of vibratory asymmetry showed that 31% to 62% of subjects displayedhigher-than-normal average values, whereas the mean values for glottal closure duration (open quotient) and periodicityof vibration fell within normal limits. The average HSV-based measures did not correlate significantly with the acousticperturbation measures, but moderate correlations were exhibited between the acoustic measures and the SDs of the HSVbasedparameters.Conclusions: The use of simultaneous, time-synchronized HSV and acoustic recordings can provide new insights intopostoperative voice production mechanisms that cannot be obtained with stroboscopic assessment.

Paper
2009
D. D. Mehta, D. D. Deliyski, S. M. Zeitels, M. Zañartu, and R. E. Hillman, “Integration of ultra high-speed color videoendoscopy with time-synchronized measures of vocal function,” Proceedings of The Triological Society (Eastern Section), 2009. Poster
S. M. Lulich, M. Zañartu, D. D. Mehta, and R. E. Hillman, “Source-filter interaction in the opposite direction: Subglottal coupling and the influence of vocal fold mechanics on vowel spectra during the closed phase,” Proceedings of Meetings on Acoustics Acoustical Society of America, vol. 6, pp. 060007, 2009. Paper
S. M. Lulich, M. Zañartu, D. D. Mehta, and R. E. Hillman, “Source-filter interaction in the opposite direction: Subglottal coupling and the influence of vocal fold mechanics on vowel spectra during the closed phase,” Proceedings of the Acoustical Society of America. 2009.
R. E. Hillman, D. D. Mehta, D. D. Deliyski, and S. M. Zeitels, “Voice production mechanisms following phonosurgical treatment of early glottic cancer,” Proceedings of the American Broncho-Esophagological Association. 2009.
2008
D. D. Mehta and R. E. Hillman, “Voice assessment: Updates on perceptual, acoustic, aerodynamic, and endoscopic imaging methods,” Current Opinion in Otolaryngology & Head and Neck Surgery, vol. 16, pp. 211-215, 2008. Publisher's VersionAbstract

PURPOSE OF REVIEW: This paper describes recent advances in perceptual, acoustic, aerodynamic, and endoscopic imaging methods for assessing voice function. RECENT FINDINGS: We review advances from four major areas. PERCEPTUAL ASSESSMENT: Speech-language pathologists are being encouraged to use the new consensus auditory-perceptual evaluation of voice inventory for auditory-perceptual assessment of voice quality, and recent studies have provided new insights into listener reliability issues that have plagued subjective perceptual judgments of voice quality. ACOUSTIC ASSESSMENT: Progress is being made on the development of algorithms that are more robust for analyzing disordered voices, including the capability to extract voice quality-related measures from running speech segments. AERODYNAMIC ASSESSMENT: New devices for measuring phonation threshold air pressures and air flows have the potential to serve as sensitive indices of glottal phonatory conditions, and recent developments in aeroacoustic theory may provide new insights into laryngeal sound production mechanisms. ENDOSCOPIC IMAGING: The increased light sensitivity of new ultra high-speed color digital video processors is enabling high-quality endoscopic imaging of vocal fold tissue motion at unprecedented image capture rates, which promises to provide new insights into the mechanisms of normal and disordered voice production. SUMMARY: Some of the recent research advances in voice function assessment could be more readily adopted into clinical practice, whereas others will require further development.

Paper
2007
D. Mehta, D. Deliyski, T. F. Quatieri, S. M. Zeitels, and R. E. Hillman, “Ultra high-speed color videoendoscopy of human voice production,” Proceedings of the American Speech-Language-Hearing Association Convention, 2007. Abstract Poster

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