Biochemical engineering harnesses living cells as miniature chemical reactors, enabling the production of designer molecules ranging from pharmaceuticals to plastics to biofuels. Live cells possess unique capabilities to manufacture complex chemical entities, yet living cells also introduce unique challenges and tradeoffs. This course introduces students to the fundamentals of biochemical engineering, including its biological underpinnings, the flow of genetic information within biological systems, the building blocks of living cells, and cellular pathways and control mechanisms. The...

This course examines the design and development of new therapeutic products. Students learn through case-based studies of product development for pharmaceuticals, biologics, medical devices, and combination therapies. The course describes the steps of biomedical product development, from conceptualization to design to manufacturing to regulatory approval and commercialization. The course discusses both technical and business factors that contribute to the success or failure of new biomedical products. Appropriate design of preclinical and clinical trials is also included in the course....

Tissue engineering is now recognized as a way to lessen the global disease burden. For example, novel methods for pancreatic islet regeneration can address diabetes; autologous cells for heart muscle regeneration can address coronary artery disease; and nerve regeneration technologies can be utilized to treat stroke. This course describes strategies of tissue engineering, and focuses on the diseases tissue engineering can address. Each lecture identifies a specific disease (coronary artery disease, stroke, diabetes) and describes tissue-engineered scaffolds that can alleviate the disease....

Tissue engineering is now recognized as a way to lessen the global disease burden: novel methods for pancreatic islet regeneration can address diabetes; autologous cells for heart muscle regeneration can address coronary artery disease; and nerve regeneration technologies can be used to treat stroke. This course describes strategies of tissue engineering, and focuses on the diseases tissue engineering can address. Each lecture identifies a specific disease (coronary artery disease, stroke, diabetes) and describes tissue-engineered scaffolds that can alleviate the disease. Students learn...

Guided reading and research in biomedical engineering.