Who am I?
I'm a research fellow in Dr. Richard Gregory's laboratory at Boston Children's Hospital/Harvard Medical School. I have a P.hD. degree in Biological Sciences with specific training in cancer biology and molecular signaling. I am originally from Quito, Ecuador.
The broad focus of my research is understanding how RNA modifications regulate RNA function in cancer, and using this knowledge to identify potential new targets for therapeutic intervention.
This image is an abstract representation of the molecular basis of oncogenic transformation. METTL-1 (the stylised “arm” in the corners) deposits the m7G mark on tRNAs, which in turn accumulate as a response to its over-expression. This is depicted as a kaleidoscope, where accumulating modified tRNAs are reflected multiple times. Going inwards, the pattern culminates in an explosion of colours, representing oncogenic transformation. (Image credit: Marzia Munafo)