I obtained my PhD in Mathematics from Technische Universität München, Munich, where I worked in the groups of Jan Hasenauer and Fabian Theis. I developed mathematical methods for the efficient calibration of large kinetic models in the context of stochasticity and cell-to-cell variability and applied them to develop novel approaches for cancer precision medicine. Prior to my PhD work, I received a Master of Science from Technische Universität München in Mathematics in Biosciences.
Currently, I am a HFSP Postdoctoral Fellow in Peter Sorger's group in the Laboratory of Systems Pharmacology at Harvard Medical School. I am developing methods to construct, calibrate and understand large kinetic models with hundreds to thousands of state variables and parameters. I apply these methods to study adaptive resistance in melanoma where I integrate structural, molecular and omics data to build detailed mechanistic models for precision medicine applications.
I served as Reviewer for PLOS Computational Biology, Complexity, BMC Systems Biology, Journal of the Royal Society Interface, CMSB2016, ISMB 2018, ISMB 2019, ISMB2020, ISMB2021.