Trio of manuscripts from the Faden Lab described the clinical, genomic and viromic landscape of patients with multiple HPV+ head and neck cancers

February 15, 2021

The incidence of HPV related head and neck cancers (HPV+ HNC) is increasing significantly in the United States. At the same time, we are now seeing patients present with, or develop, multiple HPV+ HNCs, which previously was not a clinical scenario that was thought to occur. This year The Faden Lab, along with colleagues at the University of Pittsburgh, Vanderbilt and the National Cancer Institute ...

Human Papillomavirus in Sinonasal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis

February 5, 2021

As described in a new manuscript published in the journal Cancers, 26% of sinonasal squamous cell carcinomas have detectable HPV. Interestingly, HPV prevalence was higher in subsites with high exposure to secretion flow compared to low exposure subsites and HPV prevalence followed the global distribution of HPV+ oropharyngeal squamous cell carcinoma. This manuscript is the largest analysis of HPV in...

Faden Lab Receives NIH Funding

January 29, 2021

The Faden Lab received an NIH K23 grant entitled "Dissecting temporal and spatial dynamics of immunotherapy resistance."

Head and Neck Cancer Stereotactic RadioSurgery Program

January 13, 2021

Read about the Head and Neck Cancer Stereotactic Radiosurgery Program, here

The mutational landscape of early‐ and typical‐onset oral tongue squamous cell carcinoma

January 5, 2021

An international multicenter consortium of investigators, including the Faden lab, conducted the largest study to date a characterizing the somatic mutational landscape of oral tongue cancers from young patients without known risk factors. Read the article published in Cancer, here. Read more about The mutational landscape of early‐ and typical‐onset oral tongue squamous cell carcinoma

Natalia Queenan Joins the Faden Lab

December 5, 2020

Welcome Natalia!

Natalia attended Barnard College of Columbia University, graduating cum laude with majors in Neuroscience and English. She wrote her honors thesis on noninvasive neuromodulation of cognition and motivation using focused ultrasound. ...

VTX-2337-HN-001: a neoadjuvant combination immunotherapy trial opens at Boston Medical Center

October 21, 2020

VTX-2337-HN-001 A Phase 1b Multicenter Pre-Surgical Study to Evaluate Immune Biomarker Modulation in Response to Motolimod (VTX-2337) in Combination with Nivolumab in Subjects with Resectable Squamous Cell Carcinoma of the Head and Neck (SCCHN) will be activated this week at Boston Medical Center. The study is open to patients with a new diagnosis of head and neck squamous cell carcinoma who will be undergoing surgical...

Faden Lab Recieves Harvard Catalyst Funding

August 25, 2020

The Faden lab, in collaboration with the laboratory of Shannon Stott, PhD, recieved funding from Harvard Catalyst to study how cells change across time and space in response to immunotherapy. Read more about Faden Lab Recieves Harvard Catalyst Funding

Shohreh Varmeh Joins the Faden Lab

July 1, 2020

Shohreh Varmeh received her Ph.D. in cancer biology from Karolinska Institute. Her thesis work focused on identifying genes regulated by the tumor suppressor gene p53. Her post-doctoral trainings at... Read more about Shohreh Varmeh Joins the Faden Lab

Faden Lab Receives Translational Innovator Award

June 14, 2020

The Faden lab recieved the 2020 Translational Innovator Award from the American Head and Neck Society and the American Academy of Otolaryngology- Head and Neck Surgery. This award provides... Read more about Faden Lab Receives Translational Innovator Award

Faden Laboratory

Translational Head and Neck Cancer Genomics

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