News

Trio of manuscripts from the Faden Lab described the clinical, genomic and viromic landscape of patients with multiple HPV+ head and neck cancers

February 15, 2021

The incidence of HPV related head and neck cancers (HPV+ HNC) is increasing significantly in the United States. At the same time, we are now seeing patients present with, or develop, multiple HPV+ HNCs, which previously was not a clinical scenario that was thought to occur. This year The Faden Lab, along with colleagues at the University of Pittsburgh, Vanderbilt and the National Cancer Institute ...

Read more about Trio of manuscripts from the Faden Lab described the clinical, genomic and viromic landscape of patients with multiple HPV+ head and neck cancers

Human Papillomavirus in Sinonasal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis

February 5, 2021

As described in a new manuscript published in the journal Cancers, 26% of sinonasal squamous cell carcinomas have detectable HPV. Interestingly, HPV prevalence was higher in subsites with high exposure to secretion flow compared to low exposure subsites and HPV prevalence followed the global distribution of HPV+ oropharyngeal squamous cell carcinoma. This manuscript is the largest analysis of HPV in...

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Faden Lab Receives NIH Funding

January 29, 2021
The Faden Lab received an NIH K23 grant entitled "Dissecting temporal and spatial dynamics of immunotherapy resistance."

The mutational landscape of early‐ and typical‐onset oral tongue squamous cell carcinoma

January 5, 2021
An international multicenter consortium of investigators, including the Faden lab, conducted the largest study to date a characterizing the somatic mutational landscape of oral tongue cancers from young patients without known risk factors. Read the article published in Cancer, here. Read more about The mutational landscape of early‐ and typical‐onset oral tongue squamous cell carcinoma