Positions

Staff Scientist

Job Description

This position entails overseeing the day-to-day function of the wet laboratory, mentoring medical students, technicians, and clinical research coordinators in the lab, designing and performing experiments, preparing manuscripts, and assisting with grant writing.

Required Skills and Accolades

  • Completion of PhD and Post-doc with considerable experience in cancer cell biology, cancer genomics and ideally, liquid biopsy.
  • Proficient in routine and complex laboratory techniques; has the scientific acumen to develop and learn new experimental procedures.  
  • Understanding of the state of the science to help set the direction of research projects in the lab, in collaboration with the PI.
  • Organized and meticulous.
  • Motivated to advance the science of head and neck cancer for the benefit of patients.

Ongoing Work in the Lab

  • Liquid biopsy: Liquid biopsy allows non-invasive detection and monitoring of cancer. We are designing and utilizing assays to measure analytes from head and neck cancer in the pre-diagnostic, treatment and post-treatment settings. Current work focuses on cell free DNA.
  • Mutational Processes: A subset of Head and Neck Cancers are caused by Human Papillomavirus (HPV). We are using genomic and computational techniques to dissect how HPV leads to mutation acquisition in Head and Neck Cancer by studying patterns of mutations in both head and neck cancer genomes and HPV genomes using computational approaches followed by functional interrogation in cell lines to better understand the processes that lead to mutations.
  • Viral Oncogenesis: HPV is known to cause certain types of head and neck cancer, however it’s role in other cancer types is less well understood. We are conducting studies to demonstrate that HPV is a driver of tumorigenesis in previously unrecognized tumor types.

 

 

Senior Research Technologist and Lab Manager

Job Description

This position entails working alongside the laboratory PI, Staff Scientist, clinical research coordinators, medical students and fellows to conduct translational head and neck cancer research with a focus on liquid biopsy. The overarching goal of our research is to translate findings from the laboratory to clinical advancements that address the most pressing problems faced by head and neck cancer patients.

Required Skills and Experience

  • Completion of bachelor’s degree with or without a PhD or master’s degree.
  • A minimum of 5 years lab experience in cancer cell biology or cancer genomics
  • Proficient in routine and complex laboratory techniques
  • Ability to work independently and as a team member
  • Proficiency in basic statistics, data analysis and visualization/graphing
  • Organized and meticulous
  • Ability to troubleshoot
  • Motivated to advance the science of head and neck cancer for the benefit of patients

Ongoing Work in the Lab

  • Liquid biopsy: Liquid biopsy allows non-invasive detection and monitoring of cancer. We are designing and utilizing assays to measure analytes from head and neck cancer in the pre-diagnostic, treatment and post-treatment settings. Current work focuses on cell free DNA.
  • Mutational Processes: A subset of Head and Neck Cancers are caused by Human Papillomavirus (HPV). We are using genomic and computational techniques to dissect how HPV leads to mutation acquisition in Head and Neck Cancer by studying patterns of mutations in both head and neck cancer genomes and HPV genomes using computational approaches followed by functional interrogation in cell lines to better understand the processes that lead to mutations.
  • Viral Oncogenesis: HPV is known to cause certain types of head and neck cancer, however its role in other cancer types is less well understood. We are conducting studies to demonstrate that HPV is a driver of tumorigenesis in previously unrecognized tumor types.

Principle Duties

  • Prepares and executes routine and complex experiments independently
  • Assists the PI with determining the most suitable methodology for experiments
  • Prepares lab reagents and chemicals
  • Sets up, adjusts, calibrates, maintains and troubleshoots equipment
  • Performs independent literature searches, is familiar with the state of the science
  • Organize and draft materials for manuscripts and presentations
  • Maintains and orders lab supplies
  • Helps onboard new lab members
  • Organizes weekly lab meeting

 

Medical Students and Research Fellows

The Faden lab accepts motivated medical student and international research fellows who want to spend 12 months on Head and Neck Cancer Research. Inquire by clicking the "Contact" link at the top left of the page.