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Pharmacoepidemiologic Methods for Studying the Health Effects of Drug-Drug Interactions

Citation:

Hennessy S, Leonard CE, Gagne JJ, Flory JH, Han X, Brensinger CM, Bilker WB. Pharmacoepidemiologic Methods for Studying the Health Effects of Drug-Drug Interactions. Clin Pharmacol Ther. 2016;99 (1) :92-100.

Date Published:

2016 Jan

Abstract:

A drug-drug interaction (DDI) occurs when one or more drugs affect the pharmacokinetics (the body's effect on the drug) and/or pharmacodynamics (the drug's effect on the body) of one or more other drugs. Pharmacoepidemiologic studies are the principal way of studying the health effects of potential DDIs. This article discusses aspects of pharmacoepidemiologic research designs that are particularly salient to the design and interpretation of pharmacoepidemiologic studies of DDIs.
Last updated on 05/31/2019