I focus my dissertation on how the campus context across the US postsecondary landscape shapes the experiences of upwardly mobile students and their ability to reap the health benefits of a college degree. I assess the relationship between college attendance and depression by social origins, how this association varies by individual-level and college-level characteristics, and what role psychosocial stressors play in mediating these associations. This project extends the literature on the college experience in explaining outcome heterogeneity to mental health, and assesses the role that stress, an often-hypothesized but often-untested explanation in the mobility literature, plays in this process.