Excavations at the relatively small but strategically placed site of Hirbemerdon Tepe, located along the west bank of the upper Tigris River in modern southeastern Turkey, have yielded significant results. During the Middle Bronze Age (2000–1600 B.C.E.), the site was situated in an ecologically stratified landscape that included river terraces suitable for agriculture as well as forested uplands ideal for pastoral and hunting activities. A significant result of these excavations, which were conducted by the Hirbemerdon Tepe Archaeological Project, was the discovery of a well-preserved architectural complex with associated ritual artifacts on the northern side of the high mound. This report describes and situates this Middle Bronze Age site within its geographic, cultural, and ecological context. It examines the emergence of this small regional center and investigates the role of ritual activities in the development of socially integrated communities in the frontier zone of northern Mesopotamia during the beginning of the second millennium B.C.E.