Determining the relative importance of the mechanisms of behavior change within Alcoholics Anonymous: A multiple mediator analysis


Kelly, J. F., Hoeppner, B. B., Stout, R. L., & Pagano, M. (2012). Determining the relative importance of the mechanisms of behavior change within Alcoholics Anonymous: A multiple mediator analysis. Addiction , 107 (2), 289-299.


AIMS: Evidence indicates that Alcoholics Anonymous (AA) participation reduces relapse risk but less is known about the mechanisms through which AA confers this benefit. Initial studies indicate self-efficacy, negative affect, adaptive social networks and spiritual practices are mediators of this effect, but because these have been tested in isolation, their relative importance remains elusive. This study tested multiple mediators simultaneously to help determine the most influential pathways.

DESIGN: Prospective, statistically controlled, naturalistic investigation examined the extent to which these previously identified mechanisms mediated AA attendance effects on alcohol outcomes controlling for baseline outcome values, mediators, treatment, and other confounders.

SETTING: Nine clinical sites within the United States.

PARTICIPANTS: Adults (n = 1726) suffering from alcohol use disorder (AUD) initially enrolled in a randomized study with two arms: aftercare (n = 774); and out-patient (n = 952) comparing three out-patient treatments (Project MATCH).

MEASUREMENTS: AA attendance during treatment; mediators at 9 months; and outcomes [percentage of days abstinent (PDA) and drinks per drinking day (DDD)] at 15 months.

FINDINGS: Among out-patients the effect of AA attendance on alcohol outcomes was explained primarily by adaptive social network changes and increases in social abstinence self-efficacy. Among more impaired aftercare patients, in addition to mediation through adaptive network changes and increases in social self-efficacy, AA lead to better outcomes through increasing spirituality/religiosity and by reducing negative affect. The degree to which mediators explained the relationship between AA and outcomes ranged from 43% to 67%.

CONCLUSION: While Alcoholics Anonymous facilitates recovery by mobilizing several processes simultaneously, it is changes in social factors which appear to be of primary importance.


Kelly, John FHoeppner, BettinaStout, Robert LPagano, MariaK01 DA027097/DA/NIDA NIH HHS/United StatesR21 AA016762-02/AA/NIAAA NIH HHS/United StatesR21AA016762/AA/NIAAA NIH HHS/United StatesResearch Support, N.I.H., ExtramuralEnglandAddiction (Abingdon, England)Addiction. 2012 Feb;107(2):289-99. doi: 10.1111/j.1360-0443.2011.03593.x. Epub 2011 Sep 19.

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Last updated on 02/15/2017