Publications by Year: 2019

2019
Kelly, J. F., Hoffman, L., Vilsaint, C., Weiss, R., Nierenberg, A., & Hoeppner, B. (2019). Peer support for mood disorder: Characteristics and benefits from attending the Depression and Bipolar Support Alliance mutual-help organization. Journal of Affective Disorders , 255, 127-135. Publisher's VersionAbstract

BACKGROUND:

Mood disorders (MDs) are pervasive and debilitating psychiatric conditions. Many helpful psychological and psychopharmacological treatments exist, but MD's prevalence and chronicity often means relying purely on professional care can create financial strain on individuals and healthcare systems. Also, many individuals respond only partially to professionally-delivered medical/pharmacological interventions or are unable to tolerate or adhere to them. Peer-led mutual-help organizations (MHOs) have emerged and grown in the U.S. to extend and potentiate professional efforts or otherwise address needs unmet by professional care. The Depression and Bipolar Support Alliance (DBSA) is the largest of these, but beyond observational evidence, little is known about participation or benefits. Greater knowledge could inform the field regarding clinical and public health utility of peer-driven efforts.

METHOD:

Community-based cross-sectional comparative investigation of MD individuals attending (N = 202) or not attending(N = 105) DBSA. Measures included demographics, clinical characteristics and clinical service use, and indices of symptomatology, functioning, quality of life (QOL), and psychological well-being.

RESULTS:

Compared to non-DBSA participants, DBSA participants were more likely to be male and white and trended toward greater religious affiliation (p = 0.05). DBSA participants attended meetings about twice per month with two-thirds attending for more than one year. The DBSA cohort had a much higher proportion with bipolar I disorder and reported more lifetime and past 90-day use of acute, intensive, medical services and medications. There were no between-group differences on indices of QOL or psychological well-being, but within the DBSA group, greater DBSA attendance and involvement was associated with greater QOL and well-being, and less functional impairment.

LIMITATIONS:

Cross-sectional design and regional sampling frame with unknown generalizability to national DBSA membership.

CONCLUSION:

Given the grave impact of MDs and that DBSA is freely available it may fill an important clinical and public health need by attracting and engaging MD individuals with greater functional instability and impairment. The positive association found between greater active DBSA participation and improvements in functioning and well-being, while promising, requires longitudinal investigation to formally establish the causal direction of effects.

Kelly, J. F., & Wakeman, S. (Ed.). (2019). Treating Opioid Addiction . New York: Humana Press.
Yule, A., & Kelly, J. F. (2019). Integrating treatment for co-occuring mental health conditions. Alcohol Research , 40 (1), arcr.v40.1.07. Publisher's VersionAbstract
Given the high co-occurrence between alcohol use disorder (AUD) and mental health conditions (MHCs), and the increased morbidity associated with the presence of co-occurring disorders, it is important that co-occurring disorders be identified and both disorders addressed in integrated treatment. Tremendous heterogeneity exists among individuals with co-occurring conditions, and factors related to both AUD and MHCs, including symptom type and acuity, illness severity, the chronicity of symptoms, and recovery capital, should be considered when recommending treatment interventions. This article reviews the prevalence of co-occurring AUD and MHCs, screening tools to identify individuals with symptoms of AUD and MHCs, and subsequent assessment of co-occurring disorders. Types of integrated treatment and current challenges to integrate treatment for co-occurring disorders effectively are reviewed. Innovative uses of technology to improve education on co-occurring disorders and treatment delivery are also discussed. Systemic challenges exist to providing integrated treatment in all treatment settings, and continued research is needed to determine ways to improve access to treatment.
Wakeman, S., & Kelly, J. F. (2019). Treatment and Recovery. In J. F. Kelly & S. Wakeman (Ed.), Treating Opioid Addiction . Springer Science Press.
Kelly, J. F., & Wakeman, S. (2019). Killing more than pain: Etiology and remedy for an opioid crisis. In J. F. Kelly & S. Wakeman (Ed.), Treating opioid addiction (pp. 1-18) . New York: Humana Press.
Kelly, J. F., Abry, A. W., Fallah-Sohy, N., & Bergman, B. G. (2019). Mutual-help and peer support models for opioid use disorder recovery. In J. F. Kelly & S. Wakeman (Ed.), Treating opioid addiction (pp. 139-168) . New York: Humana Press.
Bergman, B. G., Fallah-Sohy, N., Hoffman, L., & Kelly, J. F. (2019). Psychosocial approaches in the treatment of opioid use disorders. In J. F. Kelly & S. Wakeman (Ed.), Treating Opioid Addiction (pp. 109-138) . New York: Humana Press.
Kelly, J. F., Worley, M. J., & Yeterian, J. (2019). Twelve-Step Approaches. In S. A. Brown & R. Zucker (Ed.), The Oxford Handbook of Adolescent Substance Abuse (pp. 731-748) . Oxford University Press.Abstract
Twelve-step approaches to addressing substance use disorder (SUD) are unique in the treatment field in that they encompass professionally led, as well as peer-led, intervention methods. Also, in contrast to most professional treatments that have emerged from scientific theories and empirical data (e.g., cognitive-behavioral treatments), 12-step approaches have been derived, in large part, from the collective addiction and recovery experiences of laymen. Despite this, 12-step approaches have become influential in tackling SUD, with research demonstrating the clinical utility of employing such approaches among adults, and increasingly, among youth. Findings among adolescent samples indicate community 12-step mutual-help organizations, in particular, may provide a beneficial recovery-supportive social context during a life stage where such support is rare.
Ashford, R. A., Bergman, B. G., Curtis, B. L., & Kelly, J. F. (2019). Systematic Review: Digital recovery support services (D-RSS) used to support substance use disorder recovery. Human Behavior and Emerging Technologies. Human Behavior and Emerging Technologies , 2 (1), 18-32. Publisher's VersionAbstract

Substance use, misuse, and disorders (SUDs) are estimated to cost the United States over $500 billion annually. While there are effective SUD behavioral interventions and treatments, there is mounting evidence that technology‐based, digital recovery support services (D‐RSS) have the potential to prevent SUD, complement formal treatment, and improve individual recovery‐related outcomes. This preregistered systematic review focuses on D‐RSS that provide SUD recovery support through websites, smartphone applications, recovery social network sites, or any combination thereof. Data sources included studies found in searching CINAHL Plus (EBSCO), EMBASE, MEDLINE (EBSCO), Index Medicus/MEDLINE (NLM), Psychology & Behavioral Sciences Collection (EBSCO), PsycINFO (ProQuest), ProQuest Psychology Journals (ProQuest), and retrieved references. Observational, mixed‐methods, qualitative, or experimental studies, published in English, between January 1985 and January 2019, that characterized users and recovery‐related outcomes of any D‐RSS were included. The initial search yielded 5,278 abstracts. After removing duplicates, as well as reviewing titles and abstracts and removing studies not indicating an examination of recovery (i.e., treatment or prevention focused) and digital supports, 78 abstracts remained. Final included studies (n = 22) characterized international users of multiple D‐RSS types, including websites, digital recovery forums, recovery social networking sites, smartphone applications, and short messaging service texting programs. Experimental evidence was lacking as most studies were observational or qualitative in nature (n = 18). The review suggests that the evidence base for most D‐RSS is still lacking in terms of demonstrating benefit for recovery‐related outcomes. Descriptively, D‐RSS have high usage rates among engaged participants, across a range of SUD and recovery typologies and phenotypes, with 11% of U.S. adults who have resolved a SUD reporting lifetime engaging with at least one D‐RSS. D‐RSS deployment can help ameliorate barriers related to accessibility and availability of more traditional recovery supports, and may well be a valuable tool in addressing SUD and supporting recovery as uptake increases across the United States.

Kelly, J. F., Greene, M. C., Bergman, B. G., Hoeppner, B. B., & White, W. (2019). How many recovery attempts does it take to successfully resolve an alcohol or drug problem? Estimates and correlates from a national study of recovering U.S. adults. Alcoholism: Clinical and Experimental Research , 43 (7), 1533-1544. Publisher's VersionAbstract

BACKGROUND: Alcohol and other drug (AOD) problems are commonly depicted as chronically relapsing, implying multiple recovery attempts are needed prior to remission. Yet, although a robust literature exists on quit attempts in the tobacco field, little is known regarding patterns of cessation attempts related to alcohol, opioid, stimulant, or cannabis problems. Greater knowledge of such estimates and the factors associated with needing fewer or greater attempts may have utility for health policy and clinical communication efforts and approaches.

METHODS: Cross-sectional, nationally representative survey of U.S. adults (N = 39,809) who reported resolving a significant AOD problem (n = 2,002) and assessed on number of prior serious recovery attempts, demographic variables, primary substance, clinical histories, and indices of psychological distress and well-being.

RESULTS: The statistical distribution of serious recovery attempts was highly skewed with a mean of 5.35 (SD = 13.41) and median of 2 (interquartile range [IQR] = 1 to 4). Black race, prior use of treatment and mutual-help groups, and history of psychiatric comorbidity were associated with higher number of attempts, and more attempts were associated independently with greater current distress. Number of recovery attempts did not differ by primary substance (e.g., opioids vs. alcohol).

CONCLUSIONS: Estimates of recovery attempts differed substantially depending on whether the mean (5.35 recovery attempts) or median (2 recovery attempts) was used as the estimator. Implications of this are that the average may be substantially lower than anticipated because cultural expectations are often based on AOD problems being "chronically relapsing" disorders implicating seemingly endless tries. Depending on which one of these estimates is reported in policy documents or communicated in public health announcements or clinical settings, each may elicit varying degrees of help-seeking, hope, motivation, and the use of more assertive clinical approaches. The more fitting, median estimate of attempts should be used in clinical and policy communications given the distribution.

 

KEYWORDS: Alcohol Use Disorder; Opioid Use Disorder; Quit Attempts; Recovery; Remission

Hoeppner, B. B., Hoeppner, S. S., Schick, M. R., Milligan, C. M., Helmuth, E., Bergman, B. G., Abroms, L. C., et al. (2019). Using the text-messaging program SmokefreeTXT to support smoking cessation for nondaily smokers. . Substance Use & Misuse , 54 (8), 1260-1271. Publisher's VersionAbstract

INTRODUCTION: Smoking cessation interventions for nondaily smokers are needed. The current study explores the fit of the text-messaging intervention SmokefreeTXT for nondaily smokers.

METHODS: Adult nondaily smokers (N = 32; mean age = 35 ± 12, 64% female, 53% non-Hispanic White) were enrolled in SmokefreeTXT. SmokefreeTXT usage data were recorded passively, theorized mechanisms of change were assessed at baseline and 2, 6, and 12 weeks after the chosen quit day, and EMA protocols captured real-time cigarette reports at baseline, and during the first two weeks after the quit day.

RESULTS: Most participants completed the SmokefreeTXT program and responded to system-initiated inquiries, but just-in-time interaction with the program was limited. In retrospective recall at treatment end, content of the text-messages was rated as "neutral" to "helpful." Within-person change was observed in theorized mechanisms, with less craving (p < 0.01), increased abstinence self-efficacy (external: p < 0.01; internal: p < 0.01), and poorer perceptions of pros of smoking (psychoactive benefits: p < 0.01, pleasure p < 0.01; and pros: p < 0.01) reported after SmokefreeTXT initiation compared to baseline. Exploratory analyses of real-time reports of smoking (225 cigarette reports in N = 17 who relapsed) indicated that cigarettes smoked in the first two weeks after quitting were more likely to occur to reduce craving (OR = 2.21[1.21-3.72]), and less likely to occur to socialize (OR = 0.06[0.01-0.24]), between 19:00 and 23:00 (OR = 0.34[0.17-0.66]), and on Saturdays (OR = 0.59[0.35-0.99]) than prior to quitting.

CONCLUSIONS: While well accepted by nondaily smokers, SmokefreeTXT could potentially be improved by targeting cons of smoking, enhancing engagement with the just-in-time component of SmokefreeTXT, and tweaking the timing of text-messages.

 

KEYWORDS: Smoking cessation; mHealth; mechanisms of change; mobile health; text-messaging

Eddie, D. E., Hoffman, L., Vilsaint, C., Abry, A., Bergman, B. G., Hoeppner, B. B., Weinstein, C., et al. (2019). Lived experience in new models of care for substance use disorder: A systematic review of peer recovery support services and recovery coaching. Frontiers in Psychology , 10, 1052. Publisher's VersionAbstract

Peer recovery support services (PRSS) are increasingly being employed in a range of clinical settings to assist individuals with substance use disorder (SUD) and co-occurring psychological disorders. PRSS are peer-driven mentoring, education, and support ministrations delivered by individuals who, because of their own experience with SUD and SUD recovery, are experientially qualified to support peers currently experiencing SUD and associated problems. This systematic review characterizes the existing experimental, quasi-experimental, single- and multi-group prospective and retrospective, and cross-sectional research on PRSS. Findings to date tentatively speak to the potential of peer supports across a number of SUD treatment settings, as evidenced by positive findings on measures including reduced substance use and SUD relapse rates, improved relationships with treatment providers and social supports, increased treatment retention, and greater treatment satisfaction. These findings, however, should be viewed in light of many null findings to date, as well as significant methodological limitations of the existing literature, including inability to distinguish the effects of peer recovery support from other recovery support activities, heterogeneous populations, inconsistency in the definitions of peer workers and recovery coaches, and lack of any, or appropriate comparison groups. Further, role definitions for PRSS and the complexity of clinical boundaries for peers working in the field represent important implementation challenges presented by this novel class of approaches for SUD management. There remains a need for further rigorous investigation to establish the efficacy, effectiveness, and cost-benefits of PRSS. Ultimately, such research may also help solidify PRSS role definitions, identify optimal training guidelines for peers, and establish for whom and under what conditions PRSS are most effective.

Eddie, D. E., Greene, M. C., White, W. L., & Kelly, J. F. (2019). Medical burden of disease among individuals in recovery from alcohol and other drug problems in the United States. Findings from the National Recovery Survey. Journal of Addiction Medicine , 13 (5), 385-395. Publisher's VersionAbstract

Objectives: The medical sequalae of alcohol and other drug (AOD) problems exact a prodigious personal and societal cost, but little is known about the specific prevalence of such medical problems, and their relationship to quality of life and indices of well-being among those recovering from problematic AOD use. To better characterize the lifetime physical disease burden, this study investigated the prevalence of medical conditions commonly caused or exacerbated by excessive and chronic AOD exposure in a nationally representative sample of US adults in AOD problem recovery. Comparisons were made to the general US population. Demographic and clinical correlates of disease prevalence were also investigated along with the relationship between distinct medical conditions and indices of quality of life/well-being.

Methods: Cross-sectional nationally representative survey of the US adult population who report resolving an AOD problem (n = 2002). Weighted lifetime prevalence of common medical conditions were estimated and compared to the US population. Demographic and clinical correlates of medical conditions, and also overall disease burden, were estimated using logistic regression.

Results: Relative to the general population, prevalence of hepatitis C, chronic obstructive pulmonary disease, heart disease, and diabetes were elevated. Likelihood of having a lifetime diagnosis of a specific disease was related to primary substance used and sex. Quality of life was lower among those with physical disease histories relative to those without.

Conclusions: Findings highlight the increased medical burden associated with AOD problems, and speak to the need for earlier and more sustained intervention for AOD problems, greater integration of addiction treatment and primary health care, and longitudinal research to explore the complex, dynamic relationships between AOD use and physical disease.

Earnshaw, V. A., Bergman, B. G., & Kelly, J. F. (2019). Whether, when, and to whom?: An investigation of comfort with disclosing alcohol and other drug histories in a nationally representative sample of recovering persons. Journal of Substance Abuse Treatment , 101, 29-37. Publisher's VersionAbstract

 

BACKGROUND: Due to shame and fear of discrimination, individuals in, or seeking, recovery from alcohol and other drug (AOD) problems often struggle with whether, when, and to whom to disclose information regarding their AOD histories and recovery status. This can serve as a barrier to obtaining needed recovery support. Consequently, disclosure may have important implications for recovery trajectories, yet is poorly understood.

DESIGN AND SAMPLE: Cross-sectional, U.S. nationally-representative survey conducted in 2016 among individuals with resolved AOD problems (N = 1987) investigated disclosure comfort and whether disclosure comfort differed by time since problem resolution, disclosure recipient (i.e., with interpersonal intimacy), or primary substance (i.e., alcohol [51%], cannabis [11%], opioids [5%], or "other" [33%]). Predictors of disclosure comfort were also examined. Data were analyzed using LOWESS analyses, analyses of variance, and regression.

RESULTS: Overall, longer time since problem resolution was associated with greater disclosure comfort. In general, participants reported greater comfort with disclosure to family and friends, and less comfort with disclosure to co-workers, to first-time acquaintances, in public settings, and in the media, but these effects varied by primary drug with participants who had problems with alcohol and "other" drugs having significantly more disclosure comfort than those who had problems with opioids.

CONCLUSION: Dimensions of time since AOD problem resolution, interpersonal intimacy, and primary drug are significantly associated with disclosure comfort. Individuals seeking recovery may benefit from more formal coaching around disclosure, particularly those with primary opioid problems, but further research is needed to determine the desire for and effects of such coaching among those seeking recovery.

 

 

KEYWORDS: Disclosure; Recovery; Remission; Substance use disorder

Kelly, J. F., & Greene, M. C. (2019). The reality of drinking and drug using dreams: A study of the prevalence, predictors, and decay with time in recovery in a national sample of U.S. adults. Journal of Substance Abuse Treatment , 96, 12-17. Publisher's VersionAbstract

 

BACKGROUND: The meaning of unconscious dreaming has been assigned varying degrees of historical significance throughout the ages and across different cultures including in major psychological theories of psychopathology. While dreams' meaning and implications have remained controversial, not disputed is the occurrence of drinking/drug-using dreams (DDUD) when people enter recovery from a significant alcohol and other drug (AOD) problem. Typically taking the form of a relapse scenario followed by relief on awakening, such dreams can be profoundly unnerving. Beyond common anecdotal reports of these phenomena, however, very little is known about the prevalence, predictors, and decay of such dreams with time in recovery. Greater knowledge could help inform patients and providers about what to anticipate in recovery.

 

METHOD: Nationally-representative cross-sectional study of US adults (N = 39,093) who had resolved a significant AOD problem (weighted n = 2002).

 

MEASURES: DDUD prevalence/time since last DDUD; demographics; measures of clinical history.

 

RESULTS: Approximately one third (31.9%) reported experiencing DDUD which were predicted by more severe clinical history variables (earlier age of onset; prior treatment/mutual-help participation). A significant linear decay of DDUD occurrence was observed with time in recovery.

 

CONCLUSIONS: DDUD appear to occur among a substantial minority of US adults resolving significant AOD problems and are related to a more pronounced and deleterious AOD history. DDUD attenuate in frequency over time in recovery which plausibly may be indicative of increased biopsychosocial stability that reduces neurocognitive reverberation and psychological angst regarding relapse risk. Further prospective research is needed to understand the frequency, topography, content variability, and influence such dreams may have on intermediate (e.g., abstinence self-efficacy) and ultimate (substance use) outcomes.

Hennessy, E., Cristello, J., & Kelly, J. F. (2019). RCAM: A Proposed Model of Recovery Capital for Adolescents. Addiction Research & Theory , 27 (5), 429-436. Publisher's VersionAbstract

Problematic substance use is a challenge worldwide among adolescents. The recovery process requires holistic support addressing multiple and intersecting substance use risk factors; yet, there remains a lack of evidence on how to best understand and support adolescents in recovery. Recovery capital (RC) is a model that can be used to identify areas of assets that could be enhanced and barriers to address in one’s recovery process; however, this construct was generated through a study of adults who achieved natural recovery and it has since been used to frame adult recovery-related literature across the world. The primary aim of this article is to outline the rationale for and present a Recovery Capital for Adolescents Model (RCAM). The article will discuss the original recovery capital model, describe adolescent development, substance use, and recovery, and detail proposed developmental adaptations. Future qualitative and quantitative research should explore the RCAM to assess whether the proposed dimensions are complete as well as to assess its utility in clinical settings for identifying strengths and barriers for adolescents in or seeking recovery.

Jack, H. E., Oller, D., Kelly, J. F., Magidson, J. F., & Wakeman, S. E. (2019). Asking how our patients understand addiction. The American Journal of Medicine , 132 (3), 269-271. Publisher's VersionAbstract

When the President's Commission on Combating the Opioid Crisis declares “addiction [a] chronic relapsing disease of the brain”1 and calls for expanded access to care, within those statements is recognition of the influx of patients with addiction into general medicine settings for chronic disease management. The initial conversations that can shape a patient's understanding of addiction will occur more and more within primary care offices or at the bedside in the general medicine wards. The stakes are high: how patients understand their addiction may shape their health behaviors, relationship with their care team, and willingness to accept treatment.

Kelly, J. F., Whorley, M., & Yeterian, J. (2019). Twelve-step approaches. In S. A. Brown & R. Zucker (Ed.), The Oxford handbook of adolescent substance abuse (pp. 731-748) . New York: Oxford University Press.
Kelly, J. F., & Mee-Lee, D. (2019). Quality, accountability, and effectiveness in addiction treatment: The measurement-based practice model. In I. Danovitch & L. Mooney (Ed.), The assessment and treatment of addiction: Best practices and new frontiers (1st ed. pp. 207-218) . Elsevier.Abstract
A major emphasis in addiction treatment is to implement interventions that improve patients' outcomes and quality of life. Despite this worthy goal, the field has been beset by numerous challenges: immense variation in the uptake and implementation of evidence-based practices; large variability in quality care—even when evidence-based practices are adopted; and inadequate demonstration of improved patient outcomes when programs actually do deliver evidence-based practices with high fidelity. Together with the overselling of addiction treatment effectiveness by some sectors of the treatment field, these observations have led to calls for much greater accountability, including a move toward systematic measuring and reporting of patients' treatment outcomes or measurement-based practice (MBP). This chapter describes the rationale and preliminary evidence for MBP and discusses the clinical and public health implications for its widespread adoption and implementation across the addiction treatment field.
Kelly, J. F. (2019). E. M. Jellinek's Disease Concept of Alcoholism. Addiction , 114 (3), 555-559. Publisher's Version

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