Isaac Kohane, MD, PhD is the inaugural Chair of the Department of Biomedical Informatics at Harvard Medical School. He develops and applies computational techniques to address disease at multiple scales: From whole healthcare systems as “living laboratories” to the functional genomics of neurodevelopment with a focus on autism. Kohane’s i2b2 project is currently deployed internationally to over 120 major academic health centers to drive discovery research in disease and pharmacovigilance (including providing evidence on drugs which ultimately contributed to “black box”ing by the FDA). Dr. Kohane has published several hundred papers in the medical literature and authored a widely used book on Microarrays for an Integrative Genomics. He is a member of the Institute of Medicine and the American Society for Clinical Investigation.
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@zakkohane @GlobalHealthBMJ @AMIAinformatics @WHOSriLanka Thank you Isaac for highlighting. We are happy to share our learning including our many mistakes...#growthmindset
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But no growth chart deviation analyzer as capable and sophisticated as TrenDx. Yet core pediatrics function and still not addressed. Early & specific detection of height/wgt disorder bigger health impact than most genomics in general child population cc @CDCgov t.co/0WLetnHcAL
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@zakkohane @atulbutte Because connectivity in some contexts, particularly cancer, builds on changes that are similar across many of the cell lines in the LINCS data set. But this is why we're now delving further into cell-type-specific connectivity.
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Scientific payoff if you involve front-line clinicians in designing their informatics infrastructure. From a report in Sri Lanka @globalhealthbmj t.co/CC3W0vF2VR If only countries with loads of informaticians would do same @amiaInformatics @WHOSriLanka t.co/sbClEQQcHx
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Yet another one. The tide is relentless. t.co/VIpdVo1fcL
