The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future


Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, Sanderson SC, Kannry J, Zinberg R, Basford MA, et al. The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. Genet MedGenet MedGenetics in medicine : official journal of the American College of Medical Genetics. 2013.

Date Published:

Jun 6


The Electronic Medical Records and Genomics Network is a National Human Genome Research Institute-funded consortium engaged in the development of methods and best practices for using the electronic medical record as a tool for genomic research. Now in its sixth year and second funding cycle, and comprising nine research groups and a coordinating center, the network has played a major role in validating the concept that clinical data derived from electronic medical records can be used successfully for genomic research. Current work is advancing knowledge in multiple disciplines at the intersection of genomics and health-care informatics, particularly for electronic phenotyping, genome-wide association studies, genomic medicine implementation, and the ethical and regulatory issues associated with genomics research and returning results to study participants. Here, we describe the evolution, accomplishments, opportunities, and challenges of the network from its inception as a five-group consortium focused on genotype-phenotype associations for genomic discovery to its current form as a nine-group consortium pivoting toward the implementation of genomic medicine.Genet Med advance online publication 6 June 2013Genetics in Medicine (2013); doi:10.1038/gim.2013.72.


Gottesman, OmriKuivaniemi, HelenaTromp, GerardFaucett, W AndrewLi, RonglingManolio, Teri ASanderson, Saskia CKannry, JosephZinberg, RandiBasford, Melissa ABrilliant, MurrayCarey, David JChisholm, Rex LChute, Christopher GConnolly, John JCrosslin, DavidDenny, Joshua CGallego, Carlos JHaines, Jonathan LHakonarson, HakonHarley, JohnJarvik, Gail PKohane, IsaacKullo, Iftikhar JLarson, Eric BMcCarty, CatherineRitchie, Marylyn DRoden, Dan MSmith, Maureen EBottinger, Erwin PWilliams, Marc SENGP30 DK072488/DK/NIDDK NIH HHS/R01 DK088231/DK/NIDDK NIH HHS/U01 AG006781/AG/NIA NIH HHS/U01 HG004599/HG/NHGRI NIH HHS/U01 HG004603/HG/NHGRI NIH HHS/U01 HG004608/HG/NHGRI NIH HHS/U01 HG004609/HG/NHGRI NIH HHS/U01 HG004610/HG/NHGRI NIH HHS/U01 HG006375/HG/NHGRI NIH HHS/U01 HG006378/HG/NHGRI NIH HHS/U01 HG006380/HG/NHGRI NIH HHS/U01 HG006385/HG/NHGRI NIH HHS/U01 HG006388/HG/NHGRI NIH HHS/U01 HG006389/HG/NHGRI NIH HHS/U01 HG006828/HG/NHGRI NIH HHS/U01 HG006830/HG/NHGRI NIH HHS/2013/06/08 06:00Genet Med. 2013 Jun 6. doi: 10.1038/gim.2013.72.