A one-page summary report of genome sequencing for the healthy adult


Vassy JL, McLaughlin HL, MacRae CA, Seidman CE, Lautenbach D, Krier JB, Lane WJ, Kohane IS, Murray MF, McGuire AL, et al. A one-page summary report of genome sequencing for the healthy adult. Public Health GenomicsPublic Health GenomicsPublic Health Genomics. 2015;18 :123-9.


As genome sequencing technologies increasingly enter medical practice, genetics laboratories must communicate sequencing results effectively to nongeneticist physicians. We describe the design and delivery of a clinical genome sequencing report, including a one-page summary suitable for interpretation by primary care physicians. To illustrate our preliminary experience with this report, we summarize the genomic findings from 10 healthy participants in a study of genome sequencing in primary care.


Vassy, Jason LMcLaughlin, Heather LMacRae, Calum ASeidman, Christine ELautenbach, DeniseKrier, Joel BLane, William JKohane, Isaac SMurray, Michael FMcGuire, Amy LRehm, Heidi LGreen, Robert CengL30 DK089597/DK/NIDDK NIH HHS/R01-HG005092/HG/NHGRI NIH HHS/U01 HG006500/HG/NHGRI NIH HHS/U01-HG006500/HG/NHGRI NIH HHS/U19 HD077671/HD/NICHD NIH HHS/U19-HD077671/HD/NICHD NIH HHS/U41-HG006834/HG/NHGRI NIH HHS/Research Support, N.I.H., ExtramuralSwitzerland2015/01/24 06:00Public Health Genomics. 2015;18(2):123-9. doi: 10.1159/000370102. Epub 2015 Jan 21.