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Alex K. Lancaster

Evolutionary biology and complex adaptive systems

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Alex K. Lancaster

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  • Dr. Alex K. Lancaster works in the emerging discipline of evolutionary systems biology: involving a combination of empirical genomics and bioinformatics, collaborations with wet-lab experimentalists as well as mathematical modeling and simulation.

    His research investigates the interplay of evolvability and robustness: how organisms can simultaneously generate phenotypic novelty, yet be buffered against the forces of genetic and environmental change.  One major focus is understanding the cellular networks underpinning the genotype-phenotype map, and particularly the role of population-level variation in networks. A second focus is applying these insights to help identify the mechanistic underpinnings of human diseases, including cancer and autism.

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Latest News

Paper on the evolution of regulation in transcriptional networks published in Nature Communications

Monday, June 3, 2019

bioRxiv preprint on in-silico evolution of feed-forward motifs in transcriptional networks

Wednesday, April 10, 2019

Scientific ecosystem paper published in F1000 Research

Wednesday, June 20, 2018

Paper on potential prion-like element found in plants published in PNAS

Friday, July 8, 2016
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