Dr. Rotenstein is a primary care physician, healthcare leader, and researcher whose work focuses on care delivery innovation, physician wellbeing, and gender issues in medicine. She is an Instructor of Medicine at Harvard Medical School and Associate Faculty at Ariadne Labs. She was chosen as Boston's 40 under 40 in 2017 and an Aspen Spotlight Health Scholar. She is a graduate of Harvard College, Harvard Medical School, and Harvard Business School. 

In her current role as Assistant Medical Director for Population Health and Faculty Wellbeing at Brigham and Women’s Hospital, Dr. Rotenstein leads initiatives to enhance physicians’ sense of wellbeing and job doability, encourage innovation among front-line clinicians through Brigham's BCRISP Incubator, and design and implement innovative ways of delivering care to high-risk patients cared for by Brigham Health.

Dr. Rotenstein has led numerous innovative care delivery initiatives to enhance care for the most vulnerable patients. These range from developing protocols to enable frail patients to receive hospital-level care at home at CareMore Health to helping found a Transitions Primary Care Clinic for high-risk patients without a primary care doctor at Brigham and Women’s Hospital. She is also the founder of CareZooming, a social enterprise for clinicians to share best practices in ambulatory care delivery and connect with others doing similar work,

Dr. Rotenstein's research on physician and trainee mental health, published in JAMA and the Journal of General Internal Medicine has fostered increased awareness of the epidemic of depression and burnout in medical students and physicians and catalyzed action to address this public health burden. She is a nationally recognized expert on gender issues in medicine, with her research and writing on this topic featured in the New England Journal of Medicine, the Harvard Business Review, and JAMA Internal Medicine.