Check out our new fly male sterility paper, in which I identify two DNA-binding genes causing hybrid sterility, and where reproductive isolation can be seen as a Quantitative Polygenic Trait.

Hybrid sterility is a frequent outcome of crosses between closely related plant and animal species because of incompatibilities that have evolved in the parental genomes. Here, we show that a small region associated with hybrid male sterility between two closely related species of Drosophila contains two genes, both encoding DNA-binding proteins, each of which contributes to the hybrid male sterility.... Read more about DNA-binding proteins underlie male hybrid sterility in fruitflies