Madeleine is a PhD candidate in the Virology program in the Division of Medical Sciences at Harvard University. Madeleine conducts her research in Dr. Galit Alter's laboratory at the Ragon Institute of MGH, MIT and Harvard. Her primary project is studying the transfer of antibody across the placenta, from mother to child, during pregnancy and following maternal vaccination focusing on how to protect vulnerable neonates from infection. She has found a new mechanism for selective antibody transfer across the placenta, selecting for antibody N-glycosylation states, that could be harnessed for rational vaccine design. Her other projects surround understanding the pregnancy-specific immune response to vaccintion, delineating the impact of Non-neutralizing antibodies on protection against HIV acquisition and describing the longitudinal immune response to acute HIV infection.
She was recently awarded the MGH graduate student division travel award to present this research. Madeleine also studies the kinetics of antibody functionality development on acute HIV infection and the importance of non-neutralizing antibodies in HIV control, focusing on the role of antibody glycosylation. Madeleine recently won a visiting scientist scholarship from the Gates Foundation Center for TB Vaccine Discovery to conduct research with collaborators in South Africa and a CROI New Investagator scholarship to present this work at a conference.
Madeleine is also interested in the policy implications of science and is doing a secondary concentration in Science, Technology and Society at the Kennedy School. She is an active member of the Harvard Science Policy Group and was a member of the 2017 D.C. policy trip, getting the opportunity to visit many parts of the federal beauracracy and learn about job opportunities in science policy. She edited the summary of the trip.
Outside of lab, Madeleine served as co-president of LGBTQ at GSAS, a student group in Harvard's Graduate School of Arts and Sciences that seeks to advocate for LGBTQ students at the university, build community and design professionalization programs for LGBTQ students for two years. She has worked actively to revatilize and grow the club after several years of inactivity, focusing on building support for LGBTQ students and bridging the different schools at Harvard. In a similar role, she also served on Harvard Medical School's LGBTQ advisory committee for two years, helping the medical school enanct strategies to better serve all of its students, faculty and staff. Madeleine continues to work on LGBTQ advocacy at Harvard and recently published an Op-Ed in the crimson entitled Are we really welcome here?
Madeleine is also active in science communication with the Harvard group Science in the News. In Fall 2017 she gave one of the lectures, titled Politics and Prejudice: How Diversity Shapes Scientific Progress. She wrote a blog post in Fall 2017 about the security and economic implication of increased vaccine coverage entitled Vaccines: More than just your health. She will direct the spring lecture series for the group. In her work with science policy Madeleine published Op-Ed in the Times of San Diego in Fall 2017 entitled Opinion: GOP tax plan will Undermine Graduate Student Education in the Sciences.
Madeleine serves as an editor for two student journals. As the assistant editor in chief for the Journal of Science, Policy and Governance, a journal that publishes work of graduate students on issues of science policy, Madeleine is in charge of the editorial process for the two special issues that the journal publishes each year, working with collaborators and directing editorial teams. Madeleine is also an editor for the Journal of Emerging Investigators, a journal that publishes the work of middle and high school students. Madeleine works with authors and reviewers to coordinate the peer review of manuscripts and communicate results to the authors.
Madeleine has recently been elected to the first bargaining committee for the Harvard Graduate Student Union where she will work with a group of 13 elected students to negotiate a contract with the Harvard University administration.