Itch and the brain.


Pfab F, Valet M, Napadow V, Tölle T-R, Behrendt H, Ring J, Darsow U. Itch and the brain. Chem Immunol Allergy 2012;98:253-65.

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The sensation of itch - defined as unpleasant sensation inducing the urge to scratch - is processed by a network of different brain regions contributing to the encoding of sensory, emotional, attention-dependent, cognitive-evaluative and motivational patterns. Patients with atopic eczema show different activation patterns and kinetics compared to healthy volunteers. This review summarizes current studies investigating itch in the brain.

Last updated on 02/05/2015