@article {516366,
	title = {Comparative effectiveness research: does one size fit all?},
	journal = {Stat Med},
	volume = {31},
	number = {25},
	year = {2012},
	month = {2012 Nov 10},
	pages = {3062-5; discussion 3066-7},
	abstract = {In this commentary, we argue that although randomization has many benefits, not all questions we seek to answer fit into a randomized setting. Our argument utilizes the clinical setting of carotid atherosclerosis management where specific clinical questions are answered by using a variety of comparative effectiveness designs. Observational studies should not be ruled out when designing studies to address questions of comparative effectiveness.},
	keywords = {Comparative Effectiveness Research, Randomized Controlled Trials as Topic},
	issn = {1097-0258},
	doi = {10.1002/sim.5482},
	author = {Kunz, Lauren M and Yeh, Robert W and Normand, Sharon-Lise T.}
}
