@article {572936, title = {ST-segment elevation myocardial infarction in China from 2001 to 2011 (the China PEACE-Retrospective Acute Myocardial Infarction Study): a retrospective analysis of hospital data}, journal = {Lancet}, volume = {385}, number = {9966}, year = {2015}, month = {2015 01 31}, pages = {441-51}, abstract = {BACKGROUND: Despite the importance of ST-segment elevation myocardial infarction (STEMI) in China, no nationally representative studies have characterised the clinical profiles, management, and outcomes of this cardiac event during the past decade. We aimed to assess trends in characteristics, treatment, and outcomes for patients with STEMI in China between 2001 and 2011. METHODS: In a retrospective analysis of hospital records, we used a two-stage random sampling design to create a nationally representative sample of patients in China admitted to hospital for STEMI in 3 years (2001, 2006, and 2011). In the first stage, we used a simple random-sampling procedure stratified by economic-geographical region to generate a list of participating hospitals. In the second stage we obtained case data for rates of STEMI, treatments, and baseline characteristics from patients attending each sampled hospital with a systematic sampling approach. We weighted our findings to estimate nationally representative rates and assess changes from 2001 to 2011. This study is registered with ClinicalTrials.gov, number NCT01624883. FINDINGS: We sampled 175 hospitals (162 participated in the study) and 18,631 acute myocardial infarction admissions, of which 13,815 were STEMI admissions. 12,264 patients were included in analysis of treatments, procedures, and tests, and 11,986 were included in analysis of in-hospital outcomes. Between 2001 and 2011, estimated national rates of hospital admission for STEMI per 100,000 people increased (from 3{\textperiodcentered}5 in 2001, to 7{\textperiodcentered}9 in 2006, to 15{\textperiodcentered}4 in 2011; ptrend, keywords = {Aged, Aspirin, China, Female, Fibrinolytic Agents, Healthcare Disparities, Hospital Mortality, Hospitals, Rural, Hospitals, Urban, Humans, Male, Middle Aged, Myocardial Infarction, Myocardial Reperfusion, Patient Admission, Percutaneous Coronary Intervention, Quality of Health Care, Retrospective Studies, Ticlopidine, Treatment Outcome}, issn = {1474-547X}, doi = {10.1016/S0140-6736(14)60921-1}, author = {Jing Li and Li, Xi and Wang, Qing and Hu, Shuang and Wang, Yongfei and Masoudi, Frederick A and Spertus, John A and Krumholz,Harlan M. and Jiang, Lixin} }