The advent of DNA-microarrays spurred a vigorous effort to reverse engineer biological networks. Recently, these efforts have been reinvigorated by the availability of RNA-seq data from perturbed and unperturbed single cells...
Ever since my lab posted the SCoPE-MS preprint, I have been repeatedly asked about the future potential and the cost of quantifying proteins by high-throughput mass-spectrometry in single cells. I will summarize a few thoughts that hopefully will be helpful and will reduce email traffic.
Why quantify proteins and PTMs in single cells?
Single-cell RNA-seq has made great strides and become widely available and preferred method for high-throughput single-cell measurements. That is great! These...
slavovLabMany single-cell sequencing papers are published in top journals, but the paper that google scholar ranks at the top is published in a journal you may not know:
Exceptional papers do not need exceptional journals: t.co/WTNLhhGUf0