July 2019

Direct causal mechanisms

Understanding biological systems: In search of direct causal mechanisms

The advent of DNA-microarrays spurred a vigorous effort to reverse engineer biological networks. Recently, these efforts have been reinvigorated by the availability of RNA-seq data from perturbed and unperturbed single cells. In the talk below, I discuss the opportunities and limitations of using such data for inferring networks of direct causal interactions, with emphasis...

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