The advent of DNA-microarrays spurred a vigorous effort to reverse engineer biological networks. Recently, these efforts have been reinvigorated by the availability of RNA-seq data from perturbed and unperturbed single cells. In the talk below, I discuss the opportunities and limitations of using such data for inferring networks of direct causal interactions, with emphasis...
slavovLabUsing affinity purification mass spec, @SBLabUCSF, @KroganLab and colleagues defined an interaction network for all 90 human tyrosine kinases. t.co/17TrDsQlsJ
They found 1,463 mostly novel interactions between these diverse molecular complexes.
Our lab twitter account begins with a link to group trips t.co/StLfHWJFAH, such a group lunch at the restaurant with the best panoramic views of Greater Boston. (It closed after 55 years of dining.)