Single-cell mass-spectrometry detects peptide ions with high sensitivity, but time constraints limit the proteome coverage of current methods. These constraints are not fundamental, and this Perspective outlines ideas how to relax them.
slavovLabWhile much of the excitement for plexDIA is related to its potential for single-cell proteomics, it is broadly applicable to sensitive (bulk) protein analysis in general.
This point comes clearly from the highlight. t.co/JKeV9SNtvL