Research

Education
 
Ph.D. in Mechanical Engineering (2016 - 2020)
Wang-Yuhl Oh, Supervisor
Korea Advanced Institute of Science and Technology (KAIST)
Thesis: Investigation of stimulus-induced hemodynamic response in the rodent cerebral cortex using functional optical coherence tomography
 
M.S. in Mechanical Engineering (2014 - 2016)
Wang-Yuhl Oh, Supervisor
Korea Advanced Institute of Science and Technology (KAIST)
Thesis: Phase-stabilized swept-source optical coherence tomography for the study of neurovascular coupling
 
B.S. in Mechanical Engineering (2010 - 2014) 
Korea Advanced Institute of Science and Technology (KAIST)

 

Previous projects
 
a) Develpment of phase-stabilized swept-sourse optical coherence tomography (OCT) system 
Took the lead role in the development of a swept-source OCT system. The system was designed for hemodynamic imaging in the rodent brain. Developed a fiber-based 240 kHz swept laser and designed a stimulus-gated scan protocol to achieve high imaging speed. The system enabled high-speed imaging with a temporal resolution of 0.7 seconds, sufficient for imaging sensory-induced hemodynamic response. Applied phase- stabilization to the system for quantitative flow imaging (Doppler imaging) by sampling OCT signal with an optical clock generated from an additional interferometer. Developed a RF circuit that quadruples the frequency of the clock signal to increase imaging depth range of the system. This work was published in JCBFM and featured as a cover article. Click here for more details.
 
P. Shin et al. JCBFM, 2019
 
b) Imaging of the propagation of stimulus-induced vasodilation in awake mice
Took the lead role in performing OCT angiography to measure the propagation speed of vasodilation of pial arteries in awake mice with a temporal resolution of 0.02 seconds. Developed an optical intrinsic signal imaging (OISI) system which was utilized to verify the results acquired from OCT. Designed and performed all experimental procedures including animal procedures. Click here for more details.
 
c) Longitudinal imaging of cerebral microcirculation in subcortical vascular dementia using OCT angiography
Actively participated as a major role in OCT imaging and post processing procedures. Utilizing OCT angiography and Doppler imaging technique, changes in various vascular parameters such as capillary stalling and abosolute blood flow were evaluated during the disease development. Partially participated in animal procedures and performing two-photon imaging. Click here for more details.

 

Current projects
 
Will be updated by the end of August 2022!