About My Research

My research interests span multidisciplinary fields from physiological measurement, signal processing, data mining, to human aging and aging-related degenerations. The goal of my work is to promote health and wellbeing by developing new tools for understanding and predicting disease progression, monitoring health status, and guiding self-interventions to actively manage individual’s health.

I am actively working on the following topics:

(1) Harnessing the power of ambulatory data

Digital technologies are empowering us to better track and monitor our own health. What is challenging is how we are going to take advantage of the wealth of data produced every single second. We are faced with a BIG challenge in dealing with the BIG data using traditional approaches. In recent years, I have been focusing on understanding the fluctuations in physiological recordings that show promise to reflect the intrinsic functioning status of the underlying regulation systems. The idea is that the spontaneous fluctuations in physiological outputs are inherently complex while functional degeneration is accompanied by a loss of such complexity.

(2) Sleep, life style, autonomic function, and diseases

Sleep and life style are increasingly recognized as modifiable risk factors of being diseased and disease progression. The autonomic function is weighed considerably as one of the potential pathways linking individual habits and pathogenesis. Benefits of interventions targeting these factors are yet to be determined.

(3) Proactive healthcare technology

To actively manage the health status now, today, or to wait and seek for treatments until diseases come, it is time to make a decision. It is the perspective of the ‘proactive healthcare’ that to invest more time and resources up front to prevent illness and to manage chronic diseases before they progress to cause complications. It is the future of healthcare, but the future is now here already. What needs to be worked out are the how and what questions. I am trying to bridge the gaps between basic or applied research and healthcare practices, and eventually to grow them to be critical components of the new healthcare schemes. The ultimate goal is to help individuals better understand and, further, proactively manage their health status and prevent from being diseased.