Functional Limitations and Health Care Resource Utilization for Individuals with Cognitive Impairment without Dementia: Findings from a US Population-Based Survey

Citation:

J. Scott Andrews, Urvi Desai, Noam Y. Kirson, Caroline J. Enloe, Ljubica Ristovska, Sarah King, Howard G. Birnbaum, Adam S. Fleisher, Wenyu Ye, and Kristin Kahle-Wrobleski. 12/2016. “Functional Limitations and Health Care Resource Utilization for Individuals with Cognitive Impairment without Dementia: Findings from a US Population-Based Survey.” Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 1, 10. [PAPER LINK]

Abstract:

Introduction

Little is known about functional limitations and health care resource utilization of people with cognitive impairment with no dementia (CIND).

Methods

Respondents with stable or progressive cognitive impairment (CI) after the first (index) indication of CIND in 2000–2010 were identified from the Health and Retirement Study (HRS). Respondents never exhibiting CI were identified as potential controls. Propensity score–based optimal matching was used to adjust for differences in demographics and history of stroke. Differences between cohorts were assessed accounting for HRS survey design.

Results

After matching, CIND respondents had more functional limitations (difficulty with ≥1 activities of daily living: 24% vs. 15%; ≥1 instrumental activities of daily living: 20% vs. 11%) and hospital stays (37% vs. 27%) than respondents with no CI (all P < .001). Seventy five percent of CIND respondents developed dementia in the observable follow-up (median time: ∼6 years).

Discussion

Even before dementia onset, CI is associated with increased likelihood of functional limitations and greater health care resource use.

Last updated on 08/15/2020