Dr. Rubul Mout is a scientist (Research Fellow) at Harvard and BCH, working in the fields of Hematopoietic stem & T-cell engineering, protein design, and gene editing.
He is also the author of two books in Assamese.
Dr. Rubul Mout is a Fellow (Research) at Harvard Medical School, Harvard University, and at the Stem Cell Program, Boston Children’s Hospital (BCH).
Born, brought up, and educated in India, Dr. Mout moved to the United States to pursue his PhD from the University of Massachusetts, Amherst. Prior to joining Harvard/BCH, he was a Washington Research Foundation Innovation Fellow at the Institute for Protein Design, University of Washington.
At Harvard/BCH, Dr. Mout works to engineer bone marrow stem cells (also called Hematopoietic stem cells, or HSCs) to cure genetic diseases of blood origin. HSCs are the ‘mother’ cells of all blood cells that defend human bodies from diseases. Mutations in genes in the HSCs lead to hundreds of genetic diseases, from cancer to autoimmune. Dr. Mout uses various technologies, including techniques he invented in his prior research, to engineer these HSCs. In particular, he uses patient-derived induced pluripotent stem cells (iPSC) to differentiate them to HSC first, and then to produce and train T-cells that could potentially fight off many diseases.
Dr. Mout is the co-author of more than 35 research articles and the inventor of numerous technologies in gene editing and protein design. Between the years 2014-2018, he developed a technology for intracellular protein delivery and gene editing in mammalian cells, termed as the ‘E-tag’ method, which was published in a series of five research papers. In 2020, he was granted a patent for this technology by USPTO (the United States Patent and Trademark Office). His research has been featured in numerous media, including in a mini-documentary produced by LabTV and the National Institute of Health; and in a feature video by the American Chemical Society (ACS).
Dr. Mout is also the author of two books—a collection of short stories and a memoir—in his native language Assamese. His memoir depicts his extraordinary journey from a poor peasant’s family in a far remote corner of India, near the Assam-Arunachal border. The book has been an instant bestseller, and since its first publication in 2017, it has been reprinted more than 20 times (till June 2021), making it one of the most sold books in the Assamese language. The book is also included in many school/college/university curriculums across Assam. His upcoming book is the English version of his memoir.
Please visit the following pages to learn more about Dr. Mout's work: