Welcome
Ryan is a Ph.D. candidate studying translational human genomics in the Bioinformatics and Integrative Genomics program at Harvard Medical School. He is supported by an award from the Graduate Research Fellowship Program (GRFP) through the National Science Foundation (NSF).
Click here to read more about Ryan's research interests and publications, or to see his CV.
Structure Meets Function (Blog)
@ryanlcollins13
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Last week I agreed to toast James Watson for the Human Genome Project on his 90th birthday. My brief comment about his being “flawed” did not go nearly far enough. His views are abhorrent: racist, sexist, anti-semitic. I was wrong to toast. I apologize.
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... ii) once a combination of events leads to lncRNA production from an enhancer, subsequent evolution introduces binding sites for proteins that are typically associated with promoters and which may increase enhancer activity."
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Key line from discussion: "Our results suggest two possible models: i) some enhancers ... are more common substrates for evolution of new lncRNAs; or...
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Intriguing new preprint "lnc"ing long noncoding RNA splicing and eRNA production / strong enhancer activity. I need to digest this a bit more, but it's an interesting read! t.co/GiTnP6QHsO