Ryan is a Ph.D. candidate studying translational human genomics in the Bioinformatics and Integrative Genomics program at Harvard Medical School. He is supported by an award from the Graduate Research Fellowship Program (GRFP) through the National Science Foundation (NSF).
- Fascinating new PRS paper from @jorsmo &co. I particularly liked the PheWAS to show pleiotropy captured by schiz PRS. Great reminder that phenos often correlated, thus individual genetic risk factors are predictive (to varying degrees) of multiple traits. t.co/DypC6IJ0hr
- I've been working (longer than I care to admit!) on the challenging problem of predicting mammalian gene expression levels solely from genomic sequence. This work represents the furthest I could manage to get...so far! t.co/zfLavvubsX
- Each human cell packs 46 chromosomes in its nucleus. For the first time, we resolved their 3D structure in single cells with high spatial resolution. Our Dip-C paper (with @xingdong816 and @ChangChiHan of the X.S.Xie Lab, and @lh3lh3) is now in Science (t.co/N5wI3fC4Tt). t.co/MlCmi5QVkj
- sci-CAR! A scalable single cell co-assay for profiling chromatin accessibility and gene expression in the same cell(s). Method developed by the incredible @junyue_cao in collaboration with @coletrapnell lab. t.co/B8KgpwZBb1 t.co/3ThPy7qt3s