Welcome

Ryan is a Ph.D. candidate studying translational human genomics in the Bioinformatics and Integrative Genomics program at Harvard Medical School. He is supported by an award from the Graduate Research Fellowship Program (GRFP) through the National Science Foundation (NSF).

Click here to read more about Ryan's research interests and publications, or to see his CV.

Structure Meets Function (Blog)

Strength in numbers: genetic sequencing of large populations is shaping the future of medicine

Recently, I wrote a short peice for a great local science news & media outlet, Science In The News (SITN), to explain how population-scale genetic sequencing is driving major advances in precision medicine.

The article is targeted primarily for the lay public (i.e. non-specialists), so it's mostly jargon-free. It gets even better for those among us who are more visually inclined learners: a fellow PhD student at HMS, Brad Wierbowski, put together some great graphical figures to explain the core concepts (thanks Brad!).

While not a...

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@ryanlcollins13

  • eric_lander
    eric_lander Last week I agreed to toast James Watson for the Human Genome Project on his 90th birthday. My brief comment about his being “flawed” did not go nearly far enough. His views are abhorrent: racist, sexist, anti-semitic. I was wrong to toast. I apologize.
  • RyanLCollins13
    RyanLCollins13 ... ii) once a combination of events leads to lncRNA production from an enhancer, subsequent evolution introduces binding sites for proteins that are typically associated with promoters and which may increase enhancer activity."
  • RyanLCollins13
    RyanLCollins13 Key line from discussion: "Our results suggest two possible models: i) some enhancers ... are more common substrates for evolution of new lncRNAs; or...
  • RyanLCollins13
    RyanLCollins13 Intriguing new preprint "lnc"ing long noncoding RNA splicing and eRNA production / strong enhancer activity. I need to digest this a bit more, but it's an interesting read! t.co/GiTnP6QHsO