Recently, I wrote a short peice for a great local science news & media outlet, Science In The News (SITN), to explain how population-scale genetic sequencing is driving major advances in precision medicine.
The article is targeted primarily for the lay public (i.e. non-specialists), so it's mostly jargon-free. It gets even better for those among us who are more visually inclined learners: a fellow PhD student at HMS, Brad Wierbowski, put together some great graphical figures to explain the core concepts (thanks Brad!).
queenjoboOur work on germline hypermutation and the potential genetic and chemotherapeutic influences on this phenomenon from the
@mehurles group is now published! t.co/9QKrH5a5MM
Quick summary below 👇
GenomeBrowserNew track! The gnomAD Genomes Mutation Constraint track on the human GRCh38/hg38 genome. This track uses the latest gnomAD data to calculate selection pressure, using relative frequency of variation in 1 kilobase windows across the genome. Try it here:
ksamochaI'm hiring postdocs to join my team at @CGM_MGH & Broad! We study patterns of rare variation in large genomic datasets (like gnomAD), and leverage those into insights about genetic risk for disease.
If you are interested, please reach out or apply here: