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Funding and Publications

Awarded Research Funding/Grants 

 

  1. NIH grant P30ES000002: NIEHS Center pilot project: Jan 2024 - Jan 2026 

Determining the biological effects of occupational exposures in firefighters.

 Role:- Principal Investigator

  2. NIH grant P30ES000002: NIEHS Center pilot project: Oct 2018- Oct 2023 

Assessing DNA damage and repair capacity in airline flight crew.

 Role:- Principal Investigator

Publications

(https://scholar.google.com/citations?user=e2TGx6oAAAAJ&hl=en)

Publications resulted from research associate position:

  1. Brown N., …. Toprani SM. et al (2023) Tuning ultrasmall theranostic nanoparticles for MRI contrast and radiation dose amplification. Theranostics. 13(14):4711-4729.
  2. Singh R, Yu S, ….. Toprani SM. et al (2023) Radiation therapy-induced neurocognitive impairment is driven by heightened apoptotic priming in early life and prevented by blocking BAX. Cancer research. CAN-22-1337.

Publications resulted from post-doctoral research:

  1. Toprani SM, Scheibler C, et al (2022). Cancer risks from cosmic radiation exposure in flight: A review. Frontier of Public Health. 10:947068.
  2. Toprani SM, Bitounis D, Huang Q, et al. (2022) Printer center nanoparticles alter the DNA repair capacity of human bronchial airway epithelial cells. NanoImpact. 25: 100379.
  3. Toprani SM, Bitounis D, Huang Q et al. (2021) High-throughput screening platform for nanoparticle-mediated alterations of DNA repair capacity. ACS Nano. 15(3): 4728-4726.
  4. Toprani SM, Scheibler C, Nagel ZD (2020). Interplay of air travel, genome integrity and COVID-19 risk vis-a-vis flight crew. Frontier in Public Health. 8:590412.
  5. Sun T, Yang W, Toprani SM. et al (2020) Induction of immunogenic cell death in radiation-resistant breast cancer stem cells by repurposing anti-alcoholism drug disulfiram. Cell communication and signaling.18 (1), 36.
  6. Nagel ZD, Toprani SM. et al. (2019) DNA repair landscape of human blood cells. Environmental and molecular mutagenesis. 60, 24-24.

Publications resulted from graduation research:

  1. Toprani SM and Das B. (2020) Radio-adaptive response, individual radio-sensitivity, and genetic association of base excision repair gene polymorphism (hOGG1, APE1, XRCC1 and LIGASE1) in human peripheral blood mono-nuclear cells exposed to gamma radiation. Environmental and Molecular Mutagenesis. 61(5), 551-55. 
  2. Soren DC, Toprani SM, et al. (2019) Quantitation of genome damage and transcriptional profile of DNA damage response genes in human peripheral blood mononuclear cells exposed in vitro to low doses of neutron radiation. International Journal of Radiation Research. 17(1), 1-14.
  3. Toprani SM and Das B. (2015) Radio-adaptive response of base excision repair genes and proteins in human peripheral blood mononuclear cells exposed to gamma radiation. Mutagenesis. 30 (5), 663-676.
  4. Toprani SM and Das B. (2015) Role of base excision repair genes and proteins in gamma irradiated resting human peripheral blood mononuclear cells. Mutagenesis. 30 (2), 247-261.
  5. Saini D, Shelke S, Mani Vannan A, Toprani S, et al. (2012) Transcription profile of DNA damage response genes at G0 lymphocytes exposed to gamma radiation. Molecular and Cellular Biochemistry. 364(1-2), 271-281.

Corresponding author# and self-publications:

  1. Toprani SM#. and Kelkar Mane V. (2021). A short review on DNA damage and repair effects in lip cancer. Hematol Oncol Stem Cell Ther. S1658-3876(21)00007-8.
  2. Toprani SM#. and Kelkar Mane V. (2021) Role of DNA damage and repair mechanisms in uterine fibroid/leiomyomas: A review. Biology of Reproduction. 104(1), 58-70.
  3. Toprani SM#. (2020) Individual’s DNA repair capacity and COVID-19: Let’s take one step back to understand it. IJCMCR. 1(5), 001.
  4. Toprani SM#. (2020) DNA damage and repair scenario in ameloblastoma. Oral Oncology. 108, 104804.

     Published Content Writing

  1. “The Rape” published on 1st December 2019 on Medium (https://medium.com/@snehtoprani/the-rape-c1e76da213ef)
  2. “Male Menopause” published on 6th November 2018 on Medium (https://medium.com/@snehtoprani/male-menopause-db89a8c68490)
  3. “EGO!!! Do you need it and how much?” published on 4th September 2018 on Medium (https://medium.com/@snehtoprani/ego-do-you-need-it-and-how-much-faa9ff9f36d1)