Publications in 2014

32. Rotstein, B. H.; Stephenson, N. A.; Vasdev, N. & Liang, S. H. "Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics" Nat. Commun. 2014, 5, 4365. [Open Access]

  •    Highlighted on Nat Commun Facebook page as "action shot";
  •    Selected by Chemical and Engineering News for "patentpicks" on October 26, 2015;
  •    also check my 'SCIDY' page.   

spirocyclic iodonium ylide

 

31. Liang, S. H.* & Vasdev, N.* "C(sp3)-18F Bond Formation by Transition-Metal-Based [18F]Fluorination" Angew. Chem. Int. Ed. 2014, 53, 11416-8. [full-text]

ACIE highlights

 

30. Kasahara, T.; Jang, Y. J.; Racicot, L.; Panagopoulos, D.; Liang, S. H. & Ciufolini, M. A. "Iodonium metathesis reactions" Angew. Chem. Int. Ed. 2014, 53, 9637-9. [link]    [full text]

metathesis

 

29. Liang, S. H.; Yokell, D. L.; Jackson, R. N.; Rice, P. A.; Callahan, R.; Johnson, K. A.; Alagille, D.; Tamagnan, G.; Collier, T. L. & Vasdev, N. "Microfluidic continuous-flow radiosynthesis of [18F]FPEB suitable for human PET imaging" Med. Chem. Commun. 2014, 5, 432-5. [full-text]

FPEB

 

28. Liang, S. H.; Yokell, D. L.; Normandin, M. D.; Rice, P. A.; Jackson, R. N.; Shoup, T. M.; Brady, T. J.; El Fakhri, G.; Collier, T. L. & Vasdev, N. "First Human Use of a Radiopharmaceutical Prepared by Continuous-Flow Microfluidic Radiofluorination: Proof of Concept with the Tau Imaging Agent [18F]T807" Mol. Imaging 2014, 13, 1-5. [link]

  •    Featured as cover article;
  •    Highlighted on “SynthFlow” website!

T807 flow

 

27. Li, X.; Yang, C.; Wu, K.; Hu, Y.; Han, Y. & Liang, S. H. "A highly specific probe for sensing hydrogen sulfide in live cells based on copper-initiated fluorogen with aggregation-induced emission characteristics" Theranostics 2014, 4, 1233-8.  [full-text]

AIE

 

26. Holland, J. P.; Liang, S. H.; Rotstein, B. H.; Collier, T. L.; Stephenson, N. A.; Greguric, I. & Vasdev, N. "Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque" J. Labelled. Comp. Radiopharm. 2014, 57, 323-31. [link]

imaging beyond Abeta

 

25. Li, X.; Gong, Y.; Wu, K.; Liang, S. H.; Cao, J.; Yang, B.; Y., H. & Han, Y. "A highly sensitive and water soluble fluorescent probe for rapid detection of hydrogen sulfide in living cells" RSC Advances 2014, 4, 36106-9. [link]

 A highly sensitive and water soluble fluorescent probe for rapid detection of hydrogen sulfide in living cells

 

24. Rotstein, B.; Liang, S. H. & Vasdev, N. "Clinical PET Research Realized by [11C]CO2-Fixation" Molecular Imaging Gateway 2014, 8.  [link]

MI

 

23. Rotstein, B. H.; Hooker, J. M.; Woo, J.; Collier, T. L.; Brady, T. J.; Liang, S. H.* & Vasdev, N.* "Synthesis of [11C]Bexarotene by Cu-Mediated [11C]Carbon Dioxide Fixation and Preliminary PET Imaging" ACS Med. Chem. Lett. 2014, 5, 668-72. [full-text]

  •    Highlighted on journal cover!
  •    Featured on "The Cutting Edge of Chemistry - A Pharma Matters Report", Thomson Reuters, June 2014!

Abstract Image

 

22. Rotstein, B. H.; Wey, H. Y.; Shoup, T. M.; Wilson, A. A.; Liang, S. H.; Hooker, J. M. & Vasdev, N. "PET Imaging of Fatty Acid Amide Hydrolase with [18F]DOPP in Nonhuman Primates" Mol. Pharm. 2014, 11, 3832-8. [full-text]

Abstract Image