Publications in 2015

44. Wang, L.; Jacobsen, O.; Avdic, D.; Rotstein, B. H.; Weiss, I. D.; Collier, L.; Chen, X.; Vasdev, N. & Liang, S. H. "Ortho-stabilized 18F-azido click agents and application in PET imaging of single-stranded DNA aptamer" Angew. Chem. Int. Ed. 2015, 54, 12777-81.  [full-text]

  •    Highlighted on "Atlas of Science" in October 2015;
  •    Featured on “Pubfacts” website! 
  •    also check 'SCIDY' page.

 

new azide

 

43. Zheng, J.; Wang, L.; Lin, J.-H.; Xiao, J.-C. & Liang, S. H. "Difluorocarbene-derived Trifluoromethylthiolation and [18F]Trifluoromethylthiolation of Aliphatic Electrophiles" Angew. Chem. Int. Ed. 2015, 54, 13236-40.   [full-text]

  •    Highlighted on "Atlas of Science" website in October 2015!

SCF3

 

42. Jacobson, O.; Weiss, I.; Wang, L.; Wang, Z.; Yang, X.; Dewhurst, A.; Ma, Y.; Zhu, G.; Niu, G.; Kiesewetter, D. O.; Vasdev, N.; Liang, S. H.* & Chen, X.*   "18F-labeled Single-Stranded DNA Aptamer for PET Imaging of Protein Tyrosine Kinase-7 Expression" J. Nucl. Med. 2015, 56, 1780-5;    [full-text]

  •    also check 'SCIDY' page. 
Azide JNM2

 

 

41. Stephenson, N. A.; Holland, J. P.; Kassenbrock, A.; Yokell, D. L.; Livni, E.; Liang, S. H. & Vasdev, N. "Iodonium Ylide–Mediated Radiofluorination of 18F-FPEB and Validation for Human Use" J. Nucl. Med. 2015, 56, 489-92. [full-text]

  •    also check 'SCIDY' page.

FPEB JNM

 

40. Calderwood, S.; Collier, T. L.; Gouverneur, V.; Liang, S. H.* & Vasdev, N.* "Synthesis of 18F-arenes from spirocyclic iodonium(III) ylides via continuous-flow microfluidics" J. Fluorine Chem. 2015, 178, 249-253. [full-text]

  •   also check 'SCIDY' page.

Ylide flow chem

 

39. Liang, S. H. & Vasdev, N. "Total Radiosynthesis: Thinking Outside 'the Box'" Aust. J. Chem. 2015, 68, 1319-28.  [full-text]

 

38. Liang, S. H.; Southon, A. G.; Fraser, B. H.; Krause-Heuer, A. M.; Zhang, B.; Shoup, T. M.; Lewis, R.; Volitakis, I.; Han, Y.; Greguric, I.; Bush, A. I. & Vasdev, N. "Novel Fluorinated 8-Hydroxyquinoline Based Metal Ionophores for Exploring the Metal Hypothesis of Alzheimer’s Disease" ACS Med. Chem. Lett. 2015, 6, 1025-9.   [full-text]

new metal chelator

 

37. Feng, M.; Tang, B.; Liang, S. H.* & Jiang, X.* "Sulfur Containing Scaffolds in Drugs: Synthesis and Application in Medicinal Chemistry" Curr. Top. Med. Chem. 2015, 15, 15.    [full-text]

sulfur review

 

36. Ren, W.; Xu, M.; Liang, S. H.; Xiang, H.; Tang, L.; Zhang, M.; Ding, D.; Li, X.; Zhang, H. & Hu, Y. "Discovery of a novel fluorescent probe for the sensitive detection of β-amyloid Deposits" Biosens. Bioelectron. 2015, 75, 136-141.   [full-text]

pet probe

 

35. Liang, S. H.; Holland, J. P.; Stephenson, N. A.; Kassenbrock, A.; Rotstein, B. H.; Daignault, C. P.; Lewis, R.; Collier, L.; Hooker, J. M. & Vasdev, N. "PET Neuroimaging Studies of [18F]CABS13 in a Double Transgenic Mouse Model of Alzheimer’s Disease and Nonhuman Primates" ACS Chem. Neurosci. 2015, 6, 535-41. [full-text]

CABS13a

 

34. Liang, S. H.; Yokell, D. L.; Jackson, R. N.; Rice, P. A.; Livni, E.; Alagille, D.; Tamagnan, G.; Collier, T. L. & Vasdev, N., Synthesis of 3-[18F]fluoro-5-(2-pyridinylethynyl)benzonitrile ([18F]FPEB). In Radiochemical Syntheses, Vol 2:Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production, Scott, P. J. H., Ed. John Wiley & Sons, Inc.: Hoboken, New Jersey, 2015; Vol. 2, pp 41-51.

FPEB

 

33. Rotstein, B. H.; Liang, S. H.; Belov, V. V.; Livni, E.; Levine, D. B.; Bonab, A. A.; Papisov, M. I.; Perlis, R. H. & Vasdev, N. "Practical Radiosynthesis and Preclinical Neuroimaging of [11C]isradipine, a Calcium Channel Antagonist" Molecules 2015, 20, 9550-9.    [full-text]

isradipine