Publications in 2018

83. Josephson, L., Stratman, N., Liu, Y., Qian, F., Liang, S. H., Vasdev, N. and Patel, S.  "The Binding of BF-227-Like Benzoxazoles to Human α-Synuclein and Amyloid β Peptide Fibrils" Mol. Imaging, 2018, ASAP, DOI: 10.1177/1536012118796297.



82. Fu, H., Chen, Z., Josephson, L., Li, Z. and Liang, S. H.   "Positron Emission Tomography (PET) Ligand Development for Ionotropic Glutamate Receptors: Challenges and Opportunities for Radiotracer Targeting N-methyl-D-aspartate (NMDA), alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) and Kainate Receptors"  J. Med. Chem., 2018, ASAP, DOI: 10.1021/acs.jmedchem.8b00714. PubMed:


iglur rev


81. Chen, Z., Mori, W., Zhang, X., Yamasaki, T., Dunn, P. J., Zhang, G. W., Fu, H., Shao, T., Zhang, Y., Hatori, A., Ma, L., Fujinaga, M., Xie, L., Deng, X., Li, H., Yu, Q., Rong, J., Josephson, L., Ma, J., Shao, Y., Tomita, S., Zhang, M. R., and Liang, S. H.    "Synthesis and preclinical evaluation of 11C-labeled 1,3-dihydro-2H-benzo[d]imidazol-2-ones for imaging studies towards γ8-dependent transmembrane AMPA receptor regulatory protein"   Eur. J. Med. Chem., 2018, 157, 898-908. PMC article:



80. Cheng, S., Jacobson, O., Zhu, G., Chen, Z., Liang, S. H., Tian, R., Yang, Z., Niu, G., Zhu, X and Chen, X.  "PET imaging of EGFR expression using an 18F-labeled RNA aptamer"  Eur. J. Nucl. Med. Mol. Imaging, 2018, ASAP, DOI: 10.1007/s00259-018-4105-1.



79. Zheng, C., Wang, Y., Xu, Y., Chen, Z., Chen, G., and Liang, S. H.   "Ru-Photoredox-Catalyzed Decarboxylative Oxygenation of Aliphatic Carboxylic Acids through N-(acyloxy)phthalimide"  Org. Lett., 2018, 20164824-4827.   DOI:



78. Deng, X., Rong, J., Wang, L., Vasdev, N., Zhang, L., Josephson, L., and Liang, S. H.   "Chemistry for Positron Emission Tomography: Recent Advances in 11C-, 18F-, 13N- and 15O-labeling Reactions"  Angew. Chem. Int. Ed., 2018, ASAP. DOI: 10.1002/anie.201805501. PMC:

radio rev

acie cover


77. Rong, J. and Liang, S. H. "Aliphatic [18F]Fluorination Chemistry for Positron Emission Tomography", in Synthetic Organofluorine Chemistry, Springer, Hu, J. & Umemoto, T., Eds. Springer Singapore: Singapore, 2018; pp 1-14.

book chapter 18'


76. Yamasaki, T., Mori, W., Zhang, Y., Hatori, A., Fujinaga, M., Wakizaka, H., Kurihara, Y., Wang, L., Nengaki, N., Ohya, T., Liang, S. H. and Zhang, M-R. "First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [11C]SAR127303" NeuroImage, 2018, accepted. DOI: 10.1016/j.neuroimage.2018.05.015.

MAGL quant


75. Collier, T. L.; Dahl, K.; Stephenson, N. A.; Holland, J. P.; Riley, A.; Liang, S. H. and Vasdev, N.  "Recent applications of a single quadrupole mass spectrometer in 11C, 18F and radiometal chemistry" J Fluorine Chem, 2018, accepted.


74. Cheng, R.; Mori, W.; Ma, L.; Alhouayek, M.; Hatori, A.; Zhang, Y.; Ogasawara, D.; Yuan, G.; Chen, Z.; Zhang, X.; Shi, H.; Yamasaki, T.; Xie, L.; Kumata, K.; Fujinaga, M.; Nagai, Y.; Minamimoto, T.; Svensson, M.; Wang, L.; Du, Y.; Ondrechen, M.; Vasdev, N.; Cravatt, B. F.; Fowler, C.; Zhang, M-R. and Liang, S. H.  "In vitro and in vivo evaluation of 11C-labeled azetidine-carboxylates for imaging monoacylglycerol lipase by PET imaging studies"  J Med Chem, 2018, 61, 2278-2291.   DOI: 10.1021/acs.jmedchem.7b01400. [link] [full-text]



73. Krishnan, H. S.; Bernard-Gauthier, V.; Placzek, M. S.; Dahl, K.; Narayanaswami, V.; Livni, E.; Chen, Z.; Yang, J.; Collier, T. L.; Ran, C.; Hooker, J. M.; Liang, S. H. and Vasdev, N. “Metal protein-attenuating compound for PET neuroimaging: synthesis and preclinical evaluation of [11C]PBT2” Mol Pharm, 2018, 15, 695-702. DOI: 10.1021/acs.molpharmaceut.7b00936 [link]