Publications in 2022

142. Fu, H.; Rong, J.; Chen, Z.; Zhou, J.; Collier, T. and Liang, S. H. "Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors", Journal of Medicinal Chemistry, 2022, accepted. DOI: https://doi.org/10.1021/acs.jmedchem.2c00633

5HT

 

141. Haider, A.; Deng, X.; Mastromihalis, O.; Pfister, S. K.; Jeppesen, T. E.; Xiao, Z.; Pham, V.; Sun, S.; Rong, J.; Zhao, C.; Chen, J.; Li, Y.; Connors, T. R.; Davenport, A. T.; Daunais, J. B.; Hosseini, V.; Ran, W.; Christopoulos, A.; Wang, L.; Valant, C. and Liang, S. H. "Structure-Activity Relationship of Pyrazol-4-yl-Pyridine Derivatives and Identification of a Radiofluorinated Probe for Imaging the Muscarinic Acetylcholine Receptor M4", Acta Pharmaceutica Sinica B, 2022, accepted. 

M4

 

140. Ahmed, H; Gisler, L.; Elghazawy, E. H.; Keller, C.; Sippl, W.; Liang, S. H.; Haider, A and Ametamey, S. M. "Development and Validation of [3H]OF-NB1 for Preclinical Assessment of GluN1/2B Candidate Drugs", Pharmaceuticals, 2022, accepted.

3H-OFNB1

 

139. Yu, Q.; Kumata, K.; Rong, J.; Chen, Z.; Yamasaki, T.; Chen, J.; Xiao, Z.; Ishii, H.; Hiraishi, A.; Shao, T.; Zhang, Y.; Hu, K.; Xie, L.; Fujinaga, M.; Zhao, C.; Mori, W.; Collier, T.; Haider, A.; Tomita, S.; Zhang, M.-R. and Liang, S.  "Imaging of Transmembrane AMPA Receptor Regulatory Proteins by Positron Emission Tomography", Journal of Medicinal Chemistry, 2022, accepted. DOI: doi: 10.3390/ph15080960.

tarp

tarp cover

 

138. Zhang, W.; Deng, X.; Zhang, F.-X.; Lin, J.-H.; Xiao, J.-C. and Liang, S. H. "The Synthesis and 18F-Labeling of Alkenyl Sulfonyl Fluorides via an Unconventional Elimination Pathway", Organic Letters, 2022, accepted.

SO2F

OL

 

137. Bhere, D.; Choi, S. H.; van de Donk, P.; Hope, D.; Gortzak, K.; Kunnummal, A.; Khalsa, J.; Revai Lechtich, E.; Reinshagen, C.; Leon, V.; Nissar, N.; Bi, W. L.; Feng, C.; Li, H.; Zhang, Y. S.; Liang, S. H.; Vasdev, N.; Essayed, W.; Quevedo, P. V.; Golby, A.; Banouni, N.; Palagina, A.; Abdi, R.; Fury, B.; Smirnakis, S.; Lowe, A.; Reeve, B.; Hiller, A.; Chiocca, E. A.; Prestwich, G.; Wakimoto, H.; Bauer, G.; Shah, K. "Target receptor identification and subsequent treatment of resected brain tumors with encapsulated and engineered allogeneic stem cells", Nature Communications, 2022, 13, 2810.   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9120173/.

FHBG

 

136. Cheng, R.; Fujinaga, M.; Yang, J.; Rong, J.; Haider, A.; Ogasawara, D.; Van, R. S.; Shao, T.; Chen, Z.; Zhang, X.; Calderon Leon, E. R.; Zhang, Y.; Mori, W.; Kumata, K.; Yamasaki, T.; Xie, L.; Sun, S.; Wang, L.; Ran, C.; Shao, Y.; Cravatt, B.; Josephson, L.; Zhang, M. R. and Liang, S. H. "A novel monoacylglycerol lipase-targeted 18F-labeled probe for positron emission tomography imaging of brown adipose tissue in the energy network", Acta Pharmacologica Sinica, 2022, accepted.  https://pubmed.ncbi.nlm.nih.gov/35513432/.

BAT

 

135. Bengs, S.; Warnock, G. I.; Portmann, A.; Mikail, N.; Rossi, A.; Ahmed, H.; Etter, D.; Treyer, V.; Gisler, L.; Pfister, S. K.; Jie, C.; Meisel, A.; Keller, C.; Liang, S. H.; Schibli, R.; Mu, L.; Buechel, R. R.; Kaufmann, P. A.; Ametamey, S. M.; Gebhard, C.; Haider, A. Rest/stress myocardial perfusion imaging by positron emission tomography with 18F-Flurpiridaz: A feasibility study in mice. Journal of Nuclear Cardiology, 2022, doi: 10.1007/s12350-022-02968-9. 

cardio

 

134. Shao, T.; Chen, Z.; Cheng, R.; Collier, L.; Josephson, L.; Chung, R. T. and Liang, S. H. "Preliminary evaluation of [11C]MAGL-0519 as a promising PET ligand for the diagnosis of Hepatocellular carcinoma", Bioorganic Chemistry, 2022, 120, 105620. https://www.sciencedirect.com/science/article/abs/pii/S0045206822000256

HCC